Department of Chemical Engineering, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4L7.
Chem Commun (Camb). 2014 Mar 28;50(25):3306-9. doi: 10.1039/c3cc48514e.
Injectable PEG-analogue hydrogels based on poly(oligoethylene glycol methacrylate) have been developed based on complementary hydrazide and aldehyde reactive linear polymer precursors. These hydrogels display the desired biological properties of PEG, form covalent networks in situ following injection, and are easily modulated for improved control over their functionality and physiochemical properties.
基于聚（寡聚乙二醇甲基丙烯酸酯）的可注射 PEG 类似物水凝胶是基于互补的酰腙和醛反应性线性聚合物前体开发的。这些水凝胶具有 PEG 的所需生物学特性，在注射后形成共价网络，并且易于调节，以更好地控制其功能和物理化学性质。
