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[α2M球蛋白和Lpm蛋白在美国水貂器官和组织中的分布]

[Distribution of alpha 2M-globulin and Lpm-protein in the organs and tissues of the American mink].

作者信息

Skripkina L A, Serova I A, Ermolaev V I

出版信息

Arkh Anat Gistol Embriol. 1988 Feb;94(2):56-63.

PMID:2453189
Abstract

Distribution in the organs and tissues of two proteins of alpha-macroglobulin fraction, that differ in their antigenic structures, has been studied in the American mink. The both proteins (alpha 2M and Lpm) are present in hepatocytes, in cells of the follicular epithelium of the ovary, in the thymic bodies, in the alveolar macrophages of the lungs and in the splenic lymphoid nodes. Joint localization of alpha 2M and Lpm is revealed in the connective tissue of all the organs examined. The exception make the stomach and the uterine, where alpha 2M is revealed but not Lpm. The results obtained demonstrate a similar distribution of the two alpha-macroglobulins in the mink organism. They correspond to the literature data on morphofunctional topography of alpha 2M in the man. Certain individual differences in alpha 2M and Lpm localization can reflect peculiarities inherent in each of these alpha-macroglobulins of the American mink.

摘要

在美国水貂体内,对α-巨球蛋白组分中两种抗原结构不同的蛋白质在器官和组织中的分布情况进行了研究。这两种蛋白质(α2M和Lpm)存在于肝细胞、卵巢滤泡上皮细胞、胸腺小体、肺的肺泡巨噬细胞以及脾淋巴结中。在所检查的所有器官的结缔组织中均发现α2M和Lpm共同定位。例外情况是胃和子宫,在那里只发现了α2M而未发现Lpm。所获结果表明这两种α-巨球蛋白在水貂机体中的分布相似。它们与关于人类α2M形态功能定位的文献数据相符。α2M和Lpm定位的某些个体差异可能反映了美洲水貂的每种α-巨球蛋白所固有的特性。

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Murine alpha-2-macroglobulin: localization on a subpopulation of macrophages.
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