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Public Health Rev. 2012 Jan 1;34(1):71-83. doi: 10.1007/BF03391657.
2
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本文引用的文献

1
Informed consent and cluster-randomized trials.知情同意与整群随机试验。
Am J Public Health. 2012 Mar;102(3):480-5. doi: 10.2105/AJPH.2011.300389. Epub 2012 Jan 19.
2
Legal remedies for medical ghostwriting: imposing fraud liability on guest authors of ghostwritten articles.医学代笔的法律补救措施:对代笔文章的客座作者施加欺诈责任。
PLoS Med. 2010 Aug;8(8):e1001070. doi: 10.1371/journal.pmed.1001070. Epub 2011 Aug 2.
3
How the case against the MMR vaccine was fixed.反对麻腮风三联疫苗的诉讼是如何被操纵的。
BMJ. 2011 Jan 5;342:c5347. doi: 10.1136/bmj.c5347.
4
Beyond "compliance": the role of institutional culture in promoting research integrity.超越“合规”:机构文化在促进研究诚信中的作用。
Acad Med. 2010 Aug;85(8):1296-302. doi: 10.1097/ACM.0b013e3181e5f0e5.
5
Ensuring integrity in industry-sponsored research: primum non nocere, revisited.确保行业资助研究的诚信:重温“首要不伤害原则”
JAMA. 2010 Mar 24;303(12):1196-8. doi: 10.1001/jama.2010.337.
6
Funding food science and nutrition research: financial conflicts and scientific integrity.资助食品科学与营养研究:财务冲突与科学诚信。
Am J Clin Nutr. 2009 May;89(5):1285-91. doi: 10.3945/ajcn.2009.27604. Epub 2009 Apr 8.
7
Scientific integrity: critical issues in environmental health research.科学诚信:环境卫生研究中的关键问题。
Environ Health. 2008 Jun 5;7 Suppl 1(Suppl 1):S9. doi: 10.1186/1476-069X-7-S1-S9.
8
The CITI program: an international online resource for education in human subjects protection and the responsible conduct of research.CITI项目:一个关于保护人类受试者及负责任的研究行为教育的国际在线资源。
Acad Med. 2007 Sep;82(9):861-4. doi: 10.1097/ACM.0b013e31812f7770.
9
Reported goals for responsible conduct of research courses.已报告的关于负责任的研究课程行为的目标。
Acad Med. 2007 Sep;82(9):846-52. doi: 10.1097/ACM.0b013e31812f78bf.
10
The history, purpose, and future of instruction in the responsible conduct of research.科研行为规范教学的历史、目的及未来。
Acad Med. 2007 Sep;82(9):829-34. doi: 10.1097/ACM.0b013e31812f7d4d.

公共卫生、流行病学和临床研究中的伦理与科学诚信。

Ethics and Scientific Integrity in Public Health, Epidemiological and Clinical Research.

作者信息

Coughlin Steven S, Barker Amyre, Dawson Angus

机构信息

2440 16 Street, NW, Washington, DC, USA.

Research Service, Veterans Affairs Medical Center, Washington, DC, USA ; Food and Drug Administration, Rockville, MD, USA.

出版信息

Public Health Rev. 2012 Jan 1;34(1):71-83. doi: 10.1007/BF03391657.

DOI:10.1007/BF03391657
PMID:24532867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3921690/
Abstract

The ethics and scientific integrity of biomedical and public health research requires that researchers behave in appropriate ways. However, this requires more than following of published research guidelines that seek to prevent scientific misconduct relating to serious deviations from widely accepted scientific norms for proposing, conducting, and reporting research (e.g., fabrication or falsification of research data or failures to report potential conflicts of interest). In this paper we argue for a broader account of scientific integrity, one consistent with that defended by the United States Institute of Medicine, involving a commitment to intellectual honesty and personal responsibility for one's actions as a researcher and to practices consistent with the responsible conduct of research and protection of the research participants. Maintaining high standards of ethical and scientific integrity helps to maintain public trust in the research enterprise. An increasing number of authors have pointed to the importance of mentoring and education in relation to the responsible conduct of science in preventing transgressions of scientific integrity. Just like in clinical research and biomedicine, epidemiologists and other public health researchers have the responsibility to exhibit and foster the very highest standards of scientific integrity.

摘要

生物医学和公共卫生研究的伦理与科学诚信要求研究人员行为得当。然而,这不仅仅是遵循已发布的研究指南,这些指南旨在防止与严重偏离广泛接受的研究提出、开展和报告科学规范相关的科学不端行为(例如,伪造或篡改研究数据或未报告潜在利益冲突)。在本文中,我们主张对科学诚信进行更广泛的阐释,这与美国医学研究所所捍卫的观点一致,即要致力于学术诚信以及作为研究人员对自身行为承担个人责任,并践行与负责任的研究行为及保护研究参与者相一致的做法。维持高标准的伦理与科学诚信有助于维护公众对研究事业的信任。越来越多的作者指出,在预防违反科学诚信行为方面,指导和教育对于负责任的科学行为至关重要。与临床研究和生物医学一样,流行病学家和其他公共卫生研究人员有责任展现并培养最高标准的科学诚信。