抗原虫药物研发和耐药性研究的最新亮点。
Recent highlights in anti-protozoan drug development and resistance research.
机构信息
Department of Medicine, University of Washington, Seattle, WA 98195-7185, United States.
Department of Chemistry and Life Science, United States Military Academy, West Point, NY 10996, United States.
出版信息
Int J Parasitol Drugs Drug Resist. 2012 Jun 12;2:230-5. doi: 10.1016/j.ijpddr.2012.05.002. eCollection 2012 Dec.
Abstract
This article summarizes the highlights of research presented in January, 2012, at the Keystone Symposium on "Drug Discovery for Protozoan Parasites" held in Santa Fe, New Mexico. This symposium which convenes approximately every 2 years provides a forum for leading investigators around the world to present data covering basic sciences to clinical trials relating to anti-protozoan drug development and drug resistance. Many talks focused on malaria, but other protozoan diseases receiving attention included African sleeping sickness, Chagas disease, leishmaniasis, cryptosporidiosis, and amoebiasis. The new research, most of it unpublished, provided insights into the latest developments in the field.
摘要
本文总结了 2012 年 1 月在新墨西哥州圣达菲举行的“原生动物寄生虫药物发现”基石研讨会提出的研究要点。该研讨会每两年召开一次，为世界各地的主要研究人员提供了一个论坛，他们可以在此介绍涵盖基础科学到临床试验的各个方面的抗原生动物药物开发和耐药性相关数据。许多报告都集中在疟疾上，但也有其他原生动物疾病受到关注，包括非洲昏睡病、恰加斯病、利什曼病、隐孢子虫病和阿米巴病。这些新的研究大多是未发表的，为该领域的最新发展提供了深入了解。
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