Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA 94305-5107, USA.
Mayo Clin Proc. 2011 Jun;86(6):561-83. doi: 10.4065/mcp.2011.0203.
Parasitic diseases affect more than 2 billion people globally and cause substantial morbidity and mortality, particularly among the world's poorest people. This overview focuses on the treatment of the major protozoan and helminth infections in humans. Recent developments in antiparasitic therapy include the expansion of artemisinin-based therapies for malaria, new drugs for soil-transmitted helminths and intestinal protozoa, expansion of the indications for antiparasitic drug treatment in patients with Chagas disease, and the use of combination therapy for leishmaniasis and human African trypanosomiasis.
寄生虫病影响着全球超过 20 亿人口，导致大量发病和死亡，尤其是在世界上最贫困的人群中。本综述重点关注人类主要原生动物和蠕虫感染的治疗。抗寄生虫治疗的最新进展包括扩大青蒿素类药物治疗疟疾、治疗土壤传播的蠕虫和肠道原生动物的新药、扩大寄生虫病患者的抗寄生虫药物治疗适应症，以及联合治疗利什曼病和非洲人类锥虫病。
