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非精原细胞瘤性睾丸肿瘤中α-甲胎蛋白和人绒毛膜促性腺激素与淋巴结切除术结果的价值相关性

Value correlation of alpha-fetoprotein and human chorionic gonadotropin with the results of lymphadenectomy in non-seminomatous testicular tumours.

作者信息

Kausitz J, Hupka S, Ondrus D, Michalko J

机构信息

Department of Nuclear Medicine, Postgraduate Medical and Pharmaceutical Institute, Brastislava, Czechoslovakia.

出版信息

Int Urol Nephrol. 1988;20(2):147-9. doi: 10.1007/BF02550664.

DOI:10.1007/BF02550664
PMID:2454896
Abstract

In a group of 131 patients with nonseminomatous testicular tumours, the authors correlated the postorchiectomic levels of alpha-fetoprotein and human chorionic gonadotropin with the results of lymphadenectomy. They found 90.5% correlation of negative and 74% of positive levels of tumour markers with results of lymphadenectomy. In spite of 9.5% false positive and 25.7% false negative results the authors concluded that determination of alpha-fetoprotein and human chorionic gonadotropin is an important contribution to the detection of residual nonseminomatous tumour tissues after orchiectomy.

摘要

在一组131例非精原细胞瘤性睾丸肿瘤患者中,作者将睾丸切除术后甲胎蛋白和人绒毛膜促性腺激素水平与淋巴结切除术结果进行了关联分析。他们发现,肿瘤标志物阴性水平与淋巴结切除术结果的相关性为90.5%,阳性水平的相关性为74%。尽管有9.5%的假阳性和25.7%的假阴性结果,但作者得出结论,甲胎蛋白和人绒毛膜促性腺激素的测定对睾丸切除术后残余非精原细胞瘤组织的检测有重要作用。

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1
Value correlation of alpha-fetoprotein and human chorionic gonadotropin with the results of lymphadenectomy in non-seminomatous testicular tumours.非精原细胞瘤性睾丸肿瘤中α-甲胎蛋白和人绒毛膜促性腺激素与淋巴结切除术结果的价值相关性
Int Urol Nephrol. 1988;20(2):147-9. doi: 10.1007/BF02550664.
2
Alpha-fetoprotein and human chorionic gonadotropin in the management of testicular tumors.甲胎蛋白和人绒毛膜促性腺激素在睾丸肿瘤治疗中的应用
J Urol. 1977 Oct;118(4):593-6. doi: 10.1016/s0022-5347(17)58115-x.
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Tumor markers in testicular cancer.睾丸癌中的肿瘤标志物
Urol Clin North Am. 1979 Oct;6(3):613-28.
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[Diagnostic progress in testicular carcinoma].[睾丸癌的诊断进展]
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Experience with serum alpha-fetoprotein and human chorionic gonadotropin in non-seminomatous testicular tumors.血清甲胎蛋白和人绒毛膜促性腺激素在非精原细胞瘤性睾丸肿瘤中的应用经验。
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N Engl J Med. 1976 Nov 25;295(22):1237-40. doi: 10.1056/NEJM197611252952207.
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Int Urol Nephrol. 1987;19(4):415-8. doi: 10.1007/BF02550358.
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A graphical method to analyze serum tumor marker decay in nonseminomatous testis tumors.
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引用本文的文献

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本文引用的文献

1
Correlation of serum tumor markers and lymphangiography with degrees of nodal involvement in surgical stage II testis cancer.血清肿瘤标志物及淋巴管造影与手术分期为II期睾丸癌淋巴结受累程度的相关性
J Urol. 1982 Apr;127(4):683-4. doi: 10.1016/s0022-5347(17)53994-4.
2
Discordance of human chorionic gonadotropin and alpha-fetoprotein in testicular teratocarcinomas.睾丸畸胎癌中人绒毛膜促性腺激素与甲胎蛋白的不一致性
Cancer. 1973 May;31(5):1065-8. doi: 10.1002/1097-0142(197305)31:5<1065::aid-cncr2820310505>3.0.co;2-h.
3
Serum alpha fetoprotein and human chorionic gonadotropin in the diagnosis and management of nonseminomatous germ-cell testicular cancer.
血清甲胎蛋白和人绒毛膜促性腺激素在非精原细胞性生殖细胞睾丸癌诊断及治疗中的应用
N Engl J Med. 1976 Nov 25;295(22):1237-40. doi: 10.1056/NEJM197611252952207.
4
Letter: Syncytiotrophoblasts in malignant testicular tumours.
Lancet. 1976 Jul 10;2(7976):103. doi: 10.1016/s0140-6736(76)92325-4.
5
Serum alpha-foetoprotein as a marker for endodermal sinus tumour (yolk sac tumour) or a vitelline component of "teratocarcinoma".血清甲胎蛋白作为内胚窦瘤(卵黄囊瘤)或“畸胎癌”中卵黄囊成分的标志物。
Acta Pathol Microbiol Scand A. 1975 Nov;83(6):573-89. doi: 10.1111/j.1699-0463.1975.tb01385.x.