Yun Cheolmin, Oh Jaeryung, Han Ji Yun, Hwang Soon-Young, Moon Sang Woong, Huh Kuhl
Departments of *Ophthalmology, and †Biostatistics, Korea University College of Medicine, Seoul, Korea; and ‡Department of Ophthalmology, Kyung Hee University School of Medicine, Seoul, Korea.
Retina. 2015 Sep;35(9):1860-6. doi: 10.1097/IAE.0000000000000539.
To investigate peripapillary choroidal thickness (CT) outside the macula in central serous chorioretinopathy (CSC).
We reviewed the medical records of 34 patients with unilaterally symptomatic idiopathic CSC and 34 age-matched controls. Subfoveal and peripapillary CT were measured from images obtained by spectral domain optical coherence tomography. The nasal peripapillary CT of the choroid outside the macula was determined.
The subfoveal CT of CSC (369.74 ± 54.17 μm) and fellow eyes (316.18 ± 54.68 μm) of the patient group were thicker than those of the normal controls (281.90 ± 40.97 μm, all P < 0.05). The subfoveal CT in CSC was significantly thicker than those in the fellow eyes. Nasal CT was also thicker in CSC (217.59 ± 62.03 μm) and fellow eyes (206.66 ± 59.35 μm) of the patient group compared with the normal controls (179.52 ± 39.64 μm, all P < 0.05). However, there was no difference in nasal CT between CSC and fellow eyes (P = 0.150).
This result may suggest that manifest CSC occurs in patients with thick choroids both within and outside the macula, especially when subfoveal CT is increased.
研究中心性浆液性脉络膜视网膜病变(CSC)黄斑外视乳头周围脉络膜厚度(CT)。
我们回顾了34例单侧有症状的特发性CSC患者和34例年龄匹配的对照者的病历。通过光谱域光学相干断层扫描获得的图像测量黄斑下和视乳头周围CT。确定黄斑外脉络膜的鼻侧视乳头周围CT。
患者组CSC患眼的黄斑下CT(369.74±54.17μm)和对侧眼(316.18±54.68μm)比正常对照组(281.90±40.97μm)厚(均P<0.05)。CSC患眼的黄斑下CT明显厚于对侧眼。与正常对照组(179.52±39.64μm)相比,患者组CSC患眼(217.59±62.03μm)和对侧眼(206.66±59.35μm)的鼻侧CT也更厚(均P<0.05)。然而,CSC患眼和对侧眼的鼻侧CT没有差异(P=0.150)。
该结果可能提示明显的CSC发生于黄斑内外脉络膜增厚的患者,尤其是当黄斑下CT增加时。