Stinco Giuseppe, Ruscio Maurizio, Bergamo Serena, Trotter Davide, Patrone Pasquale
Department of Clinical and Experimental Pathology and Medicine, Institute of Dermatology, University of Udine School of Medicin, Ospedale "San Michele," Piazza Rodolone 1, Gemona del Friuli, 33013 Udine, Italy.
Clinical Laboratory and Microbiology Department, Hospital of San Daniele del Friuli, San Daniele, Italy.
ScientificWorldJournal. 2014 Jan 16;2014:414505. doi: 10.1155/2014/414505. eCollection 2014.
Lyme Borreliosis is a multisystemic infection caused by spirochetes of Borrelia burgdorferi sensu lato complex. The features of Lyme Borreliosis may differ in the various geographical areas, primarily between the manifestations found in America and those found in Europe and Asia.
to describe the clinical features of Lyme Borreliosis in an endemic geographic area such as Friuli-Venezia Giulia in the Northeastern part of Italy.
The medical records of patients resulted seropositive for Borrelia burgdorferi have been retrospectively recorded and analyzed.
Seven hundred and five patients met the inclusion criteria, 363 males and 342 females. Erythema migrans was the most common manifestation, detected in 437 patients. Other classical cutaneous manifestations included 58 cases of multiple erythema migrans, 7 lymphadenosis benigna cutis, and 18 acrodermatitis chronica atrophicans. The musculoskeletal system was involved in 511 patients. Four hundred and sixty patients presented a neurological involvement. Flu-like symptoms preceded or accompanied or were the only clinical feature in 119 patients.
The manifestations of Lyme borreliosis recorded in this study are similar to the ones of other endemic areas in Europe, even if there are some peculiar features which are different from those reported in Northern Europe and in the USA.
莱姆病是一种由伯氏疏螺旋体狭义复合体的螺旋体引起的多系统感染。莱姆病的特征在不同地理区域可能有所不同，主要体现在美洲、欧洲和亚洲发现的临床表现之间。
描述意大利东北部弗留利-威尼斯朱利亚等地方性流行区域莱姆病的临床特征。
对伯氏疏螺旋体血清学呈阳性的患者的病历进行回顾性记录和分析。
705例患者符合纳入标准，其中男性363例，女性342例。游走性红斑是最常见的表现，437例患者中检测到。其他典型的皮肤表现包括58例多发游走性红斑、7例良性皮肤淋巴结病和18例慢性萎缩性肢端皮炎。511例患者的肌肉骨骼系统受累。460例患者出现神经受累。119例患者出现流感样症状，这些症状先于或伴随或为唯一的临床特征。
本研究中记录的莱姆病表现与欧洲其他地方性流行区域的表现相似，尽管存在一些与北欧和美国报道不同的独特特征。
