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中国西藏地区儿童头发中硒含量与大骨节病分布的关系

Relationship between selenium concentration in child hair and the distribution of Kashin-Beck disease in Tibet, China.

作者信息

Li Shunjiang, Yang Linsheng, Wang Wuyi, Li Yonghua, Li Hairong, Xirao Ruodeng

机构信息

Environmental School, Beijing Normal University, Beijing, 100875, China.

出版信息

Front Med China. 2007 May;1(2):223-5. doi: 10.1007/s11684-007-0043-1.

DOI:10.1007/s11684-007-0043-1
PMID:24557682
Abstract

The focus of this study is to determine the relationship between selenium (Se) concentrations in child hair and the distribution of Kashin-Beck disease (KBD) in Tibet. The hair of children in typical KBD-affected areas and non-disease areas was collected, and its Se concentrations were measured by atomic fluorescent spectrometry. The Se concentrations in child hair were (0.13±0.04) and (0.18±0.07) μg/g respectively in KBD areas and non-disease areas respectively, which are significantly different. In areas supplemented with Se in Tibet, the Se concentration of hair in KBD-affected areas was higher than that in non-diseased areas, being (0.28±0.03) and (0.18±0.04) μg/g respectively. There is a close relationship between the Se concentrations in hair and KBD distribution. Se supplement increase the Se concentrations in the human body. Appropriate Se supplementation is important to prevent KBD in Tibet.

摘要

本研究的重点是确定西藏儿童头发中硒(Se)浓度与大骨节病(KBD)分布之间的关系。收集了典型大骨节病病区和非病区儿童的头发,采用原子荧光光谱法测定其硒浓度。大骨节病病区和非病区儿童头发中的硒浓度分别为(0.13±0.04)μg/g和(0.18±0.07)μg/g,差异有统计学意义。在西藏补硒地区,大骨节病病区头发中的硒浓度高于非病区,分别为(0.28±0.03)μg/g和(0.18±0.04)μg/g。头发中的硒浓度与大骨节病分布密切相关。补硒可提高人体中的硒浓度。适当补硒对预防西藏大骨节病很重要。

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引用本文的文献

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Progress of Selenium Deficiency in the Pathogenesis of Arthropathies and Selenium Supplement for Their Treatment.硒缺乏在关节病发病机制中的研究进展及其硒补充治疗。
Biol Trace Elem Res. 2022 Oct;200(10):4238-4249. doi: 10.1007/s12011-021-03022-4. Epub 2021 Nov 15.
2
Environmental selenium in the Kaschin-Beck disease area, Tibetan Plateau, China.中国青藏高原克山病地区的环境硒。
Environ Geochem Health. 2011 Oct;33(5):495-501. doi: 10.1007/s10653-010-9366-y. Epub 2010 Nov 30.