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解毒剂:欧洲预防蜱传疾病的抗蜱疫苗。

ANTIDotE: anti-tick vaccines to prevent tick-borne diseases in Europe.

作者信息

Sprong Hein, Trentelman Jos, Seemann Ingar, Grubhoffer Libor, Rego Ryan O M, Hajdušek Ondřej, Kopáček Petr, Šíma Radek, Nijhof Ard M, Anguita Juan, Winter Peter, Rotter Bjorn, Havlíková Sabina, Klempa Boris, Schetters Theo P, Hovius Joppe W R

机构信息

The National Institute of Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

出版信息

Parasit Vectors. 2014 Feb 21;7:77. doi: 10.1186/1756-3305-7-77.

Abstract

Ixodes ricinus transmits bacterial, protozoal and viral pathogens, causing disease and forming an increasing health concern in Europe. ANTIDotE is an European Commission funded consortium of seven institutes, which aims to identify and characterize tick proteins involved in feeding and pathogen transmission. The knowledge gained will be used to develop and evaluate anti-tick vaccines that may prevent multiple human tick-borne diseases. Strategies encompassing anti-tick vaccines to prevent transmission of pathogens to humans, animals or wildlife will be developed with relevant stakeholders with the ultimate aim of reducing the incidence of tick-borne diseases in humans.

摘要

蓖麻硬蜱传播细菌、原生动物和病毒病原体,导致疾病,在欧洲对健康构成越来越大的威胁。ANTIDotE是一个由欧洲委员会资助的、由七个研究所组成的联盟,旨在识别和表征蜱虫在取食和病原体传播过程中涉及的蛋白质。所获得的知识将用于开发和评估可能预防多种人类蜱传疾病的抗蜱疫苗。将与相关利益攸关方制定包括抗蜱疫苗在内的战略,以防止病原体传播给人类、动物或野生动物,最终目标是降低人类蜱传疾病的发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a40/3933510/7a1357949e66/1756-3305-7-77-1.jpg

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