Jon Ali F, Cheema Ahmad R, Khan Atif N, Raptopoulos Vassilios, Hauser Thomas, Nasser Imad, Welty Francine K, Karellas Andrew, Clouse Melvin E
Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Department of Radiology, University of Massachusetts Medical School, Worcester, MA, USA.
Clin Imaging. 2014 May-Jun;38(3):259-64. doi: 10.1016/j.clinimag.2014.01.005. Epub 2014 Jan 17.
To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S).
Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU.
There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05).
Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.
与肝脏脾脏法（CTL/S、CTL-S）相比，开发一种使用计算机断层扫描（CT）脂肪百分比指数（CTFPI）量化肝脏脂肪的简化方法。
对89例（超重、肥胖、严重肥胖）患者进行肝脏非增强CT扫描以量化脂肪，使用以下公式：CTFPI = [(65 - 患者HU)/65]×100，正常肝脏 = 65 HU。
CTFPI与使用CTL/S（r = -0.901）、CTL-S（r = -0.911）评估肝脏脂肪的标准方法之间存在强线性相关性。与其他两组相比，严重肥胖组的肝脏HU和CTFPI有显著差异（P <.05）。
显著相关性表明在适当校准的扫描仪中，这两种方法具有相同的诊断准确性。
