使用非增强CT脂肪百分比指数评估肥胖患者群体的肝脏脂肪
Assessment of liver fat in an obese patient population using noncontrast CT fat percent index.
作者信息
Jon Ali F, Cheema Ahmad R, Khan Atif N, Raptopoulos Vassilios, Hauser Thomas, Nasser Imad, Welty Francine K, Karellas Andrew, Clouse Melvin E
机构信息
Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Department of Radiology, University of Massachusetts Medical School, Worcester, MA, USA.
出版信息
Clin Imaging. 2014 May-Jun;38(3):259-64. doi: 10.1016/j.clinimag.2014.01.005. Epub 2014 Jan 17.
OBJECTIVE
To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S).
METHODS
Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU.
RESULTS
There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05).
CONCLUSION
Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.
目的
与肝脏脾脏法（CTL/S、CTL-S）相比，开发一种使用计算机断层扫描（CT）脂肪百分比指数（CTFPI）量化肝脏脂肪的简化方法。
方法
对89例（超重、肥胖、严重肥胖）患者进行肝脏非增强CT扫描以量化脂肪，使用以下公式：CTFPI = [(65 - 患者HU)/65]×100，正常肝脏 = 65 HU。
结果
CTFPI与使用CTL/S（r = -0.901）、CTL-S（r = -0.911）评估肝脏脂肪的标准方法之间存在强线性相关性。与其他两组相比，严重肥胖组的肝脏HU和CTFPI有显著差异（P <.05）。
结论
显著相关性表明在适当校准的扫描仪中，这两种方法具有相同的诊断准确性。
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