Vloet Timo D, Großheinrich Nicola, Konrad Kerstin, Freitag Christine, Herpertz-Dahlmann Beate
Klinik für Kinder- und Jugendpsychiatrie, RWTH Aachen.
Z Kinder Jugendpsychiatr Psychother. 2014 Mar;42(2):95-107; quiz 107-8. doi: 10.1024/1422-4917/a000276.
The last few years have seen much research on girls with conduct disorder (CD). This article summarizes the gender-specific data regarding prevalence, differences with respect to symptomatology (e.g., subtypes of aggression, callous-unemotional (cu)-traits), and it presents data on the autonomic and neuroendocrine stress system as well as genetic, neurocognitive, and neuroimaging data. Differences in the impact of environmental factors on boys and girls for the development of CD are discussed. Taken together, the data indicate that there is great overlap in symptomatology, personality traits, and neurobiological aberrations in girls and boys with CD. Since fewer girls than boys exhibit CD symptomatology, further investigations on CD in girls might help to identify resilience factors that could improve future therapeutic interventions.
在过去几年里，针对患有品行障碍（CD）的女孩开展了大量研究。本文总结了关于患病率的性别特异性数据、症状学方面的差异（例如攻击行为的亚型、冷酷无情特质），并呈现了自主神经和神经内分泌应激系统的数据以及基因、神经认知和神经影像学数据。文中还讨论了环境因素对男孩和女孩患CD发展影响的差异。综合来看，数据表明患有CD的女孩和男孩在症状学、人格特质和神经生物学异常方面存在很大重叠。由于表现出CD症状的女孩比男孩少，对女孩CD的进一步研究可能有助于识别恢复力因素，从而改善未来的治疗干预措施。
