脓肿分枝杆菌中质粒介导的耐药性证明。
Demonstration of plasmid-mediated drug resistance in Mycobacterium abscessus.
作者信息
Matsumoto Cristianne Kayoko, Bispo Paulo José Martins, Santin Katiane, Nogueira Christiane Lourenço, Leão Sylvia Cardoso
机构信息
Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de São Paulo, São Paulo, Brazil.
出版信息
J Clin Microbiol. 2014 May;52(5):1727-9. doi: 10.1128/JCM.00032-14. Epub 2014 Feb 26.
Abstract
Plasmid-mediated kanamycin resistance was detected in a strain of Mycobacterium abscessus subsp. bolletii responsible for a nationwide epidemic of surgical infections in Brazil. The plasmid did not influence susceptibility to tobramycin, streptomycin, trimethoprim-sulfamethoxazole, clarithromycin, or ciprofloxacin. Plasmid-mediated drug resistance has not been described so far in mycobacteria.
摘要
在一株引起巴西全国性外科感染流行的脓肿分枝杆菌博列蒂亚种中检测到质粒介导的卡那霉素耐药性。该质粒不影响对妥布霉素、链霉素、甲氧苄啶-磺胺甲恶唑、克拉霉素或环丙沙星的敏感性。迄今为止，分枝杆菌中尚未描述过质粒介导的耐药性。
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