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射血分数保留的心力衰竭的治疗干预措施:当前证据总结

Therapeutic interventions for heart failure with preserved ejection fraction: A summary of current evidence.

作者信息

Asrar ul Haq Muhammad, Wong Chiew, Mutha Vivek, Anavekar Nagesh, Lim Kwang, Barlis Peter, Hare David L

机构信息

Muhammad Asrar ul Haq, Chiew Wong, Vivek Mutha, Nagesh Anavekar, Peter Barlis, Department of Cardiology, The Northern Hospital, Epping, VIC 3076, Australia.

出版信息

World J Cardiol. 2014 Feb 26;6(2):67-76. doi: 10.4330/wjc.v6.i2.67.

Abstract

Heart failure with preserved ejection fraction (HFPEF) is common and represents a major challenge in cardiovascular medicine. Most of the current treatment of HFPEF is based on morbidity benefits and symptom reduction. Various pharmacological interventions available for heart failure with reduced ejection fraction have not been supported by clinical studies for HFPEF. Addressing the specific aetiology and aggressive risk factor modification remain the mainstay in the treatment of HFPEF. We present a brief overview of the currently recommended therapeutic options with available evidence.

摘要

射血分数保留的心力衰竭(HFpEF)很常见,是心血管医学中的一项重大挑战。目前,HFpEF的大多数治疗都是基于降低发病率和减轻症状。各种用于射血分数降低的心力衰竭的药物干预措施尚未得到HFpEF临床研究的支持。针对特定病因和积极改变危险因素仍然是HFpEF治疗的主要方法。我们简要概述了目前推荐的治疗选择及现有证据。

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