Suleiman Amal K
Pharmacy School, Department of Clinical Pharmacy, Princess Nora bint Abdul Rahman University.
Glob J Health Sci. 2013 Dec 20;6(2):138-44. doi: 10.5539/gjhs.v6n2p138.
Eight percent of pregnancies involve hypertensive disorders, which can have serious complications for mothers and children. There has only been minimal research into hypertension in pregnancy in developing countries, including Jordan. Therefore, this study aimed to identify how frequent certain risk factors that apply to hyper-tensive disorders during pregnancy were among women in the Jordanian capital of Amman. A prospective case-control study was conducted on 184 Jordanian pregnant patients with hypertensive disorders and 172 age-matched control subjects recruited from the maternity ward of a tertiary public hospital in Amman city; they were followed-up until 85 days after the birth (late puerperium). A standardized questionnaire pilot-tested was completed by participants that included demographic data and known risk factors for hypertension in pregnancy. Statistical analysis SPSS was conducted to compare the frequency of risk factors using Fisher's exact test, chi-square, Student's t-tests, as well as multivariate logistic regression was conducted to identify independent risk factors. The results showed that chronic hypertension, prenatal hypertension, family history of preeclampsia, diabetes, high BMI, nulliparity, previous preeclampsia history and low education level were identified as risk factors for hypertensive disorders in pregnancy in this population; Moreover, diabetes, chronic hypertension and family history of preeclampsia were found to be independent risk factors. The results of the study contribute to the currently limited knowledge about the modifiable risk factors for hypertensive disorders during pregnancy among the Jordanian population, and could therefore be extremely useful for clinicians providing prenatal care.
8%的孕期会出现高血压疾病,这可能对母亲和孩子产生严重并发症。在包括约旦在内的发展中国家,针对孕期高血压的研究极少。因此,本研究旨在确定约旦首都安曼的女性中,适用于孕期高血压疾病的某些风险因素出现的频率。对184名患有高血压疾病的约旦孕妇和172名年龄匹配的对照对象进行了一项前瞻性病例对照研究,这些对照对象是从安曼市一家三级公立医院的产科病房招募的;对她们进行随访直至产后85天(产褥晚期)。参与者完成了一份经过预测试的标准化问卷,其中包括人口统计学数据和已知的孕期高血压风险因素。使用SPSS进行统计分析,采用Fisher精确检验、卡方检验、学生t检验来比较风险因素的频率,并进行多因素逻辑回归以确定独立风险因素。结果表明,慢性高血压、产前高血压、子痫前期家族史、糖尿病、高体重指数、未生育、既往子痫前期病史和低教育水平被确定为该人群孕期高血压疾病的风险因素;此外,糖尿病、慢性高血压和子痫前期家族史被发现是独立风险因素。该研究结果有助于补充目前约旦人群中关于孕期高血压疾病可改变风险因素的有限知识,因此对提供产前护理的临床医生可能极为有用。