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不同人群中的高血压:一份纽约州医疗补助计划临床指南文件。

Hypertension in diverse populations: a New York State Medicaid clinical guidance document.

作者信息

Wrobel Mark J, Figge James J, Izzo Joseph L

机构信息

Department of Pharmacy Practice, State University of New York at Buffalo, Buffalo, NY, USA.

出版信息

J Am Soc Hypertens. 2011 Jul-Aug;5(4):208-29. doi: 10.1016/j.jash.2011.05.003.

Abstract

The New York State Medicaid Prescriber Education Program (PEP) is a partnership between the Department of Health and state academic institutions that provides prescribers with an evidence-based, noncommercial source of the latest objective information about pharmaceuticals. This article, detailing treatment of uncomplicated hypertension in diverse populations, represents one of the first large-scale PEP initiatives. The main risk factors for hypertension are age and obesity. Disparities in hypertension risk and outcomes among diverse populations are now believed to be more a function of personal habits, socioeconomic status and psychosocial factors rather than race, ethnicity, or genetics. Blood pressure is controllable in most patients, and all patients should be treated according to best practices. Lifestyle modification, especially diet and exercise, should be encouraged, but most patients will require more than one antihypertensive medication to control blood pressure. Combination therapy with an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker plus thiazide-type diuretic or dihydropyridine calcium channel blocker is largely universal in efficacy. Improved provider-patient partnership and communication is important to blood pressure lowering success, and cultural sensitivity should be taken into account where applicable.

摘要

纽约州医疗补助开方者教育项目(PEP)是卫生部与州学术机构之间的合作项目,旨在为开方者提供基于证据的、关于药品的最新客观信息的非商业来源。本文详细介绍了不同人群中单纯性高血压的治疗方法,是PEP最早的大规模项目之一。高血压的主要风险因素是年龄和肥胖。现在认为,不同人群中高血压风险和治疗结果的差异更多地取决于个人习惯、社会经济地位和心理社会因素,而非种族、民族或基因。大多数患者的血压是可控的,所有患者都应按照最佳实践进行治疗。应鼓励改变生活方式,特别是饮食和运动,但大多数患者需要不止一种抗高血压药物来控制血压。血管紧张素转换酶抑制剂或血管紧张素受体阻滞剂与噻嗪类利尿剂或二氢吡啶类钙通道阻滞剂联合治疗在疗效上基本通用。改善医患合作关系和沟通对于成功降低血压很重要,在适用的情况下应考虑文化敏感性。

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