Khan Muhammad Shahzeb, Bawany Faizan Imran, Ahmed Muhammad Umer, Hussain Mehwish, Khan Asadullah, Lashari Muhammad Nawaz
Dow Medical College.
Glob J Health Sci. 2013 Dec 27;6(2):189-95. doi: 10.5539/gjhs.v6n2p189.
The objective of our study was to assess betel nut usage as one of the major risk factors associated with coronary artery disease.
This case control study consisted of 300 controls and 300 cases. A structured questionnaire was administered to the participants to assess consumption of betel nut and confounding variables. A respondent was considered a regular consumer of betel nut if he/she consumed one or more pieces of betel nut every day for a period of greater than 6 months.
About 8 in 10 betel nut chewers developed coronary artery disease. After adjusting for diabetes and hypertension, the odds ratio analysis depicted 7.72 times greater likelihood for coronary artery disease in patients who chewed betel nut for more than 10 years.
Our study concludes that betel nut chewing is a significant risk factor leading to the development of coronary artery disease.
我们研究的目的是评估槟榔使用作为与冠状动脉疾病相关的主要风险因素之一。
这项病例对照研究包括300名对照者和300名病例。向参与者发放一份结构化问卷,以评估槟榔消费情况和混杂变量。如果一名受访者连续6个月以上每天食用一片或多片槟榔,那么他/她就被视为槟榔的经常消费者。
大约十分之八的槟榔咀嚼者患上了冠状动脉疾病。在对糖尿病和高血压进行校正后,比值比分析显示,咀嚼槟榔超过10年的患者患冠状动脉疾病的可能性高出7.72倍。
我们的研究得出结论,咀嚼槟榔是导致冠状动脉疾病发生的一个重要风险因素。