十二指肠假性黑变病。1例的内镜、组织学及超微结构研究

Pseudomelanosis of the duodenum. Endoscopic, histologic, and ultrastructural study of a case.

作者信息

Castellano G, Canga F, Lopez I, Colina F, Gutierrez J, Costa R, Solis-Herruzo J A

机构信息

Service of Gastroenterology, Hospital 1 de Octubre, Universidad Complutense, Madrid, Spain.

出版信息

J Clin Gastroenterol. 1988 Apr;10(2):150-4. doi: 10.1097/00004836-198804000-00009.

DOI:10.1097/00004836-198804000-00009

PMID:2458403

Abstract

We present the endoscopic, microscopic, and histochemical studies of a patient with pseudomelanosis of the duodenum. The pigment was located mainly in the lysosomes of macrophages in the lamina propria and was heterogeneous, showing features of melanin, pseudomelanin, and hemosiderin. The origin of this pigment remains unknown, but antihypertensive medication may have played a role.

摘要

我们展示了一位十二指肠假性黑变病患者的内镜、显微镜及组织化学研究结果。色素主要位于固有层巨噬细胞的溶酶体中，呈异质性，具有黑色素、假黑色素和含铁血黄素的特征。这种色素的来源尚不清楚，但抗高血压药物可能起到了一定作用。