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J Paediatr Child Health. 2013 Aug;49(8):664-70. doi: 10.1111/jpc.12261. Epub 2013 Jun 7.
2
New molecular virus detection methods and their clinical value in lower respiratory tract infections in children.新型分子病毒检测方法及其在儿童下呼吸道感染中的临床价值。
Paediatr Respir Rev. 2013 Mar;14(1):38-45. doi: 10.1016/j.prrv.2012.04.002. Epub 2012 May 5.
3
Epidemiology of multiple respiratory viruses in childcare attendees.婴幼儿照护者中多种呼吸道病毒的流行病学。
J Infect Dis. 2013 Mar 15;207(6):982-9. doi: 10.1093/infdis/jis934. Epub 2013 Jan 3.
4
Diagnostic value of respiratory virus detection in symptomatic children using real-time PCR.实时 PCR 检测呼吸道病毒在有症状儿童中的诊断价值。
Virol J. 2012 Nov 19;9:276. doi: 10.1186/1743-422X-9-276.
5
Contribution of the Portuguese Laboratory Network for the Diagnosis of Influenza A(H1N1)pdm09 infection during the 2009/10 and 2010/11 influenza seasons.葡萄牙流感诊断实验室网络在 2009/10 年和 2010/11 年流感季节中对甲型 H1N1pdm09 感染的贡献。
Euro Surveill. 2012 Jul 5;17(27):20211. doi: 10.2807/ese.17.27.20211-en.
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The efficacy of intranasal live attenuated influenza vaccine in children 2 through 17 years of age: a meta-analysis of 8 randomized controlled studies.鼻腔内接种减毒活流感疫苗在 2 至 17 岁儿童中的疗效:8 项随机对照研究的荟萃分析。
Vaccine. 2012 Jan 20;30(5):886-92. doi: 10.1016/j.vaccine.2011.11.104. Epub 2011 Dec 7.
7
Viral respiratory infections during the 2009 influenza A(H1N1) outbreak in the West Midlands Region, UK.英国西米德兰兹地区 2009 年甲型 H1N1 流感大流行期间的病毒性呼吸道感染。
Epidemiol Infect. 2012 Sep;140(9):1551-6. doi: 10.1017/S0950268811002251. Epub 2011 Nov 11.
8
Simultaneous molecular detection and confirmation of influenza AH5, with internal control.同时进行甲型H5流感病毒的分子检测及确认,并设有内部对照。
Methods Mol Biol. 2011;665:161-81. doi: 10.1007/978-1-60761-817-1_10.
9
Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology.婴幼儿呼吸道病毒感染:病因、临床症状、病毒学和免疫学。
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Mutational analysis of cis-acting RNA signals in segment 7 of influenza A virus.甲型流感病毒第7节段中顺式作用RNA信号的突变分析。
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通过家长报告改善葡萄牙学龄前儿童的流感监测。

Improving influenza surveillance in Portuguese preschool children by parents' report.

作者信息

Paixão Paulo, Piedade Cátia, Papoila Ana, Caires Iolanda, Pedro Catarina, Santos Madalena, Silvestre Maria José, Brum Laura, Nunes Baltazar, Guiomar Raquel, Curran Martin D, Carvalho Ana, Marques Teresa, Neuparth Nuno

机构信息

CEDOC, Faculdade de Ciências Médicas, FCM, Universidade Nova de Lisboa, 1169-056, Lisboa, Portugal,

出版信息

Eur J Pediatr. 2014 Aug;173(8):1059-65. doi: 10.1007/s00431-014-2285-7. Epub 2014 Mar 6.

DOI:10.1007/s00431-014-2285-7
PMID:24599798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7087149/
Abstract

UNLABELLED

Influenza surveillance is usually based on nationally organized sentinel networks of physicians and on hospital reports. This study aimed to test a different report system, based on parents' phone contact to the research team and in home collection of samples by a dedicated team. The identification of influenza and other respiratory viruses in children who attended a Hospital Emergency Department was also recorded. Real-time PCR and reverse transcription PCR were performed for influenza A and B, parainfluenza 1-4, adenovirus, human metapneumovirus, respiratory syncytial virus A and B, rhinovirus, enterovirus, group 1 coronaviruses, group 2 coronaviruses, and human bocavirus. One hundred children were included, 64 from the day care centers and 36 from the Hospital. Overall, 79 samples were positive for at least one respiratory virus. Influenza A (H3) was the virus most frequently detected: 25 cases, 20 of these in children under 5 years of age (ten from day care centers and ten who went to the hospital) which was higher than those reported by the National Influenza Surveillance Programme for this age.

CONCLUSION

The results obtained in this study suggest that a surveillance system based on parents' reports could complement the implanted system of the National Influenza Surveillance Programme.

摘要

未标注

流感监测通常基于全国组织的医生哨点网络和医院报告。本研究旨在测试一种不同的报告系统,该系统基于家长与研究团队的电话联系以及由专门团队进行的家庭样本采集。还记录了在医院急诊科就诊的儿童中流感和其他呼吸道病毒的鉴定情况。对甲型和乙型流感、副流感1 - 4型、腺病毒、人偏肺病毒、呼吸道合胞病毒A和B、鼻病毒、肠道病毒、1组冠状病毒、2组冠状病毒和人博卡病毒进行了实时PCR和逆转录PCR检测。纳入了100名儿童,其中64名来自日托中心,36名来自医院。总体而言,79份样本至少对一种呼吸道病毒呈阳性。甲型流感(H3)是最常检测到的病毒:25例,其中20例为5岁以下儿童(10例来自日托中心,10例前往医院),这高于国家流感监测计划针对该年龄段报告的病例数。

结论

本研究获得的结果表明,基于家长报告的监测系统可以补充国家流感监测计划已实施的系统。