Mangano Carlo, Iaculli Flavia, Piattelli Adriano, Mangano Francesco, Shibli Jamil Awad, Perrotti Vittoria, Iezzi Giovanna
Int J Periodontics Restorative Dent. 2014 Mar-Apr;34(2):e43-9. doi: 10.11607/prd.1832.
The aim of this case series was a clinical, histologic, and histomorphometric evaluation of calcium carbonate in sinus elevation procedures. Sinus augmentation was performed in the atrophic maxillae of 24 subjects using calcium carbonate. Six months after the regeneration procedures, 68 implants were placed and clinically followed for 1 to 5 years, depending on the placement timing. At the last implant placement procedure, 8 bone cores were harvested and processed for histology. After a 6-month healing period, sinuses grafted with calcium carbonate showed a mean vertical bone gain of 6.93 ± 0.23 mm. The histomorphometric analysis revealed 15% ± 3% residual grafted biomaterial, 28% ± 2% newly formed bone, and 57% ± 2% marrow spaces. The implant survival rate was 98.5%. It can be concluded that calcium carbonate was shown to be clinically suitable for sinus elevation procedures after 1 to 5 years of follow-up and histologically biocompatible and osteoconductive.
本病例系列的目的是对碳酸钙在鼻窦提升手术中的临床、组织学和组织形态计量学进行评估。使用碳酸钙对24名受试者的萎缩上颌骨进行鼻窦增高术。再生手术后6个月，植入68颗种植体，并根据植入时间进行1至5年的临床随访。在最后一次种植体植入手术时，采集8个骨芯并进行组织学处理。经过6个月的愈合期，用碳酸钙移植的鼻窦平均垂直骨增量为6.93±0.23毫米。组织形态计量学分析显示，残余移植生物材料为15%±3%，新形成骨为28%±2%，骨髓腔为57%±2%。种植体存活率为98.5%。可以得出结论，经过1至5年的随访，碳酸钙在临床上适用于鼻窦提升手术，并且在组织学上具有生物相容性和骨传导性。
