Department of Biomedical, Surgical and Dental Sciences, University of Milano, 20122 Milano, Italy.
Retrieval Bank of the Laboratory for Undemineralized Hard Tissue Histology, University "G. D'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
Int J Environ Res Public Health. 2022 Jun 28;19(13):7942. doi: 10.3390/ijerph19137942.
In more than three decades of work of the Retrieval Bank of the Laboratory for Undemineralized Hard Tissue Histology of the University of Chieti-Pescara in Italy, many types of biomaterials were received and evaluated. The present retrospective review aimed to evaluate the histological and biological aspects of the evaluated bone substitute biomaterials.
In the present study, the authors prepared a retrospective analysis after the screening of some databases (PubMed, Scopus, and EMBASE) to find papers published from the Retrieval Bank of the Laboratory for Undermineralized Hard Tissue Histology of the University of Chieti-Pescara analyzing only the papers dealing with bone substitute biomaterials and scaffolds, in the form of granules and block grafts, for bone regeneration procedures.
Fifty-two articles were found, including in vitro, in vivo, and clinical studies of different biomaterials. These articles were evaluated and organized in tables for a better understanding.
Over three decades of studies have made it possible to assess the quality of many bone substitute biomaterials, helping to improve the physicochemical and biological properties of the biomaterials used in daily clinical practice.
在意大利基耶蒂-佩斯卡拉大学未脱矿硬组织组织学实验室检索库超过三十年的工作中，收到并评估了许多类型的生物材料。本回顾性研究旨在评估评估的骨替代生物材料的组织学和生物学方面。
在本研究中，作者在筛选了一些数据库（PubMed、Scopus 和 EMBASE）后，进行了回顾性分析，以找到仅分析涉及骨替代生物材料和支架的论文，这些论文以颗粒和块状移植物的形式用于骨再生程序，这些论文均来自基耶蒂-佩斯卡拉大学未脱矿硬组织组织学实验室检索库。
共发现 52 篇文章，包括不同生物材料的体外、体内和临床研究。这些文章进行了评估并组织成表格，以便更好地理解。
三十多年的研究使我们能够评估许多骨替代生物材料的质量，有助于改善在日常临床实践中使用的生物材料的物理化学和生物学特性。
