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Intermediate filaments in the cochleas of normal and mutant (w/wv, sl/sld) mice.

作者信息

Schrott A, Egg G, Spoendlin H

机构信息

Department of Otorhinolaryngology, University Hospital, Innsbruck, Austria.

出版信息

Arch Otorhinolaryngol. 1988;245(4):250-4. doi: 10.1007/BF00463937.

DOI:10.1007/BF00463937
PMID:2460075
Abstract

Using monoclonal and polyclonal antibodies to intermediate filaments in the cochleas of normal and mutant mice, we were able to distinguish between different cell types of the stria vascularis. Immunostaining for vimentin was found in the intermediate and basal cells of the stria vascularis of the normal mice. In contrast, vimentin was seen to stain only the basal cells in the mutant mice, confirming our previous findings of the absence of intermediate cells in these cases of hereditary deafness. Immunostaining for cytokeratin was identical in both the mutant and control mice.

摘要

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本文引用的文献

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Tyrosinase in human skin: demonstration of its presence and of its role in human melanin formation.人皮肤中的酪氨酸酶:其存在及在人黑色素形成中作用的证明
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Intermediate filaments as mechanical integrators of cellular space.中间丝作为细胞空间的机械整合器。
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Intermediate filaments in malignant melanomas. Identification and use as marker in surgical pathology.恶性黑色素瘤中的中间丝。在外科病理学中的鉴定及用作标志物
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Pigment anomaly-associated inner ear deafness.色素异常相关性内耳性耳聋
Acta Otolaryngol. 1987 May-Jun;103(5-6):451-7.
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Intermediate filaments in the newborn inner ear of the mouse.新生小鼠内耳中的中间丝。
ORL J Otorhinolaryngol Relat Spec. 1986;48(2):98-106. doi: 10.1159/000275854.
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Cytoskeletal organization of the human inner ear.人类内耳的细胞骨架组织
Acta Otolaryngol Suppl. 1987;437:5-76. doi: 10.3109/00016488709099002.
10
Immunohistochemical demonstration of the co-expression of vimentin and cytokeratin(s) in the guinea pig cochlea.波形蛋白和细胞角蛋白在豚鼠耳蜗中共表达的免疫组织化学证明
Arch Otorhinolaryngol. 1987;244(1):66-8. doi: 10.1007/BF00453494.