Tekatas Aslan, Pamuk Omer N
Department of Neurology, Trakya University Medical Faculty, Edirne, Turkey.
Int J Rheum Dis. 2015 Jan;18(1):58-62. doi: 10.1111/1756-185X.12323. Epub 2014 Feb 25.
To assess the prevalence of restless leg syndrome (RLS) in patients with ankylosing spondylitis (AS) and to investigate factors potentially associated with RLS.
One hundred and thirty patients diagnosed with AS according to modified New York criteria and 91 age- and sex-matched healthy control subjects were included in this study. The diagnosis of RLS was made according to the criteria of the International RLS Study Group. The factors associated with RLS were evaluated. Electrophysiological procedures were performed in a group of patients with RLS.
RLS was significantly more common in patients with AS (30.8%) than in healthy controls (13.2%). When AS patients with RLS were compared with AS patients without RLS, it was seen that peripheral arthritis, uveitis, anemia, smoking and polyneuropathy were significantly higher in the former group.
RLS is common in patients with AS and iron deficiency, smoking and small fiber neuropathy seem to be possible causes.
评估强直性脊柱炎（AS）患者中不宁腿综合征（RLS）的患病率，并调查可能与RLS相关的因素。
本研究纳入了130例根据改良纽约标准诊断为AS的患者以及91例年龄和性别匹配的健康对照者。根据国际RLS研究组的标准进行RLS的诊断。评估与RLS相关的因素。对一组RLS患者进行了电生理检查。
AS患者中RLS的发生率（30.8%）显著高于健康对照组（13.2%）。将伴有RLS的AS患者与不伴有RLS的AS患者进行比较时，发现前一组的外周关节炎、葡萄膜炎、贫血、吸烟和多发性神经病明显更多。
RLS在AS患者中很常见，缺铁、吸烟和小纤维神经病变似乎是可能的病因。
