Reisenbuckler Carol
Radiol Technol. 2014 Mar-Apr;85(4):391-410; quiz 411-3.
Multiple myeloma is the most common primary bone cancer among U.S. adults aged 70 years and older, and the incidence of the disease is increasing. Despite significant advances in treatment since the 1960s, multiple myeloma remains a challenging disease to diagnose and treat. Several medical diagnostic imaging examinations play important roles. This article reviews the biological basis of multiple myeloma, clinical features and diagnosis of the disease, and imaging and treatment protocols. The article also discusses unusual presentations of multiple myeloma.
多发性骨髓瘤是美国70岁及以上成年人中最常见的原发性骨癌，且该疾病的发病率正在上升。尽管自20世纪60年代以来治疗取得了重大进展，但多发性骨髓瘤仍然是一种诊断和治疗都具有挑战性的疾病。几种医学诊断成像检查发挥着重要作用。本文综述了多发性骨髓瘤的生物学基础、该疾病的临床特征与诊断以及成像和治疗方案。本文还讨论了多发性骨髓瘤的不典型表现。
