Umezawa Keitaro, Citterio Daniel, Suzuki Koji
Graduate School of Medicine, The University of Tokyo.
Anal Sci. 2014;30(3):327-49. doi: 10.2116/analsci.30.327.
This review summarizes progress in the field of near-infrared (NIR) fluorophores achieved during the last decade from the viewpoint of chemistry. Those compounds are of wide interest in bioanalysis and bioimaging, such as in vivo fluorescence imaging. Particular focus is placed on the recent developments of BODIPY and rhodamine derivatives, which belong to the most evolved NIR fluorophores. The data compiled in this review, including the chemical structures and optical properties of all compounds introduced, provide readers of this article with an overview of the field of NIR fluorophores.
本综述从化学角度总结了近十年来近红外（NIR）荧光团领域所取得的进展。这些化合物在生物分析和生物成像领域，如体内荧光成像中具有广泛的应用。特别关注了BODIPY和罗丹明衍生物的最新进展，它们属于发展最为成熟的近红外荧光团。本综述汇编的数据，包括所介绍的所有化合物的化学结构和光学性质，为本文读者提供了近红外荧光团领域的概述。
