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骨盆肉瘤广泛切除术后同种异体骨盆移植重建的长期结果。

Long-term results of reconstruction with pelvic allografts after wide resection of pelvic sarcomas.

作者信息

Ayvaz Mehmet, Bekmez Senol, Mermerkaya M Ugur, Caglar Omur, Acaroglu Emre, Tokgozoglu A Mazhar

机构信息

Department of Orthopaedics and Traumatology, Faculty of Medicine, Hacettepe University, 06100 Ankara, Turkey.

Department of Orthopaedics and Traumatology, Dr. Sami Ulus Training and Research Hospital, 06100 Ankara, Turkey.

出版信息

ScientificWorldJournal. 2014 Jan 27;2014:605019. doi: 10.1155/2014/605019. eCollection 2014.

Abstract

Reconstruction after the resection of a pelvic tumor is a challenging procedure in orthopedic oncology. The main advantage of allograft reconstruction is restoration of the bony architecture of the complex pelvic region. However, high complication rates such as infection and allograft resorption had been reported in the literature. In this study, we aimed to retrospectively review nine patients treated with pelvic resection and structural pelvic allograft reconstruction. Functional results, complications, and survival of the patients and the allografts were evaluated. At a mean follow-up of 79 months, three patients were dead. Major complications were detected in eight of the nine patients. Infection (four of the nine patients) and allograft resorption (three of the nine patients) were the most common causes of failure. The cumulative survival of the patients was 66.7 percent at 70 months. However, allograft survival was only 26.7 percent at 60 months. Mean MSTS score was 69. In conclusion, we suggest that other reconstruction options should be preferred after pelvic resections because of the high complication rates associated with massive allograft reconstruction.

摘要

骨盆肿瘤切除术后的重建是骨肿瘤学中一项具有挑战性的手术。同种异体骨重建的主要优点是恢复复杂骨盆区域的骨结构。然而,文献报道了诸如感染和同种异体骨吸收等高并发症发生率。在本研究中,我们旨在回顾性分析9例行骨盆切除及结构性骨盆同种异体骨重建治疗的患者。评估了患者的功能结果、并发症以及患者和同种异体骨的生存率。平均随访79个月时,3例患者死亡。9例患者中有8例出现主要并发症。感染(9例患者中的4例)和同种异体骨吸收(9例患者中的3例)是最常见的失败原因。患者在70个月时的累积生存率为66.7%。然而,同种异体骨在60个月时的生存率仅为26.7%。平均肌肉骨骼肿瘤学会(MSTS)评分为69分。总之,由于大块同种异体骨重建相关的高并发症发生率,我们建议骨盆切除术后应优先选择其他重建方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d7a/3925599/2aa5f01e775a/TSWJ2014-605019.001.jpg

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