Mundel P, Elger M, Sakai T, Kriz W
Anatomisches Institut der Universität Heidelberg, Federal Republic of Germany.
Cell Tissue Res. 1988 Oct;254(1):183-7. doi: 10.1007/BF00220032.
The mesangial matrix of the rat glomerulus was studied by transmission electron microscopy in specimens preserved by a modified technique, which avoids osmium tetroxide but uses tannic acid as a contrasting agent. It can be demonstrated that microfibrils are a major component of the normal glomerular mesangial matrix. They are non-branching tubular structures with a hollow centre, an undefined length and a thickness of approximately 15 nm. Microfibrils make up a dense fibrillar network interconnecting mesangial cells and glomerular basement membrane.
采用一种改良技术保存标本，通过透射电子显微镜对大鼠肾小球系膜基质进行了研究。该技术避免使用四氧化锇，而是使用鞣酸作为对比剂。结果表明，微原纤维是正常肾小球系膜基质的主要成分。它们是无分支的管状结构，中心中空，长度不定，厚度约为15纳米。微原纤维构成一个致密的纤维网络，将系膜细胞和肾小球基底膜相互连接起来。
