Arreghini Marco, Manzoni Gian Mauro, Castelnuovo Gianluca, Santovito Cristina, Capodaglio Paolo
Rehabilitation Unit, Istituto Auxologico Italiano IRCCS, Piancavallo (VB), Italy.
Psychology Research Laboratory, Istituto Auxologico Italiano IRCCS, Piancavallo (VB), Italy; Department of Psychology, Catholic University of Milan, Milan, Italy.
PLoS One. 2014 Mar 11;9(3):e91392. doi: 10.1371/journal.pone.0091392. eCollection 2014.
A possible link between fibromyalgia (FM) and obesity has been recently suggested but very scanty data on the prevalence of FM in obese populations are available. The aims of the present cross-sectional study were: 1) to estimate the prevalence of FM in a population of obese patients undergoing rehabilitation and 2) to investigate the effect of FM on obese patients' functional capacities. One hundred and thirty Italian obese (Body Mass Index, BMI ≥ 30) patients admitted to hospital for 1-month rehabilitation treatment took part in the study. All participants were interviewed by a rheumatologist according to the 2010 American College of Rheumatology (ACR) diagnostic criteria for FM. At admission and discharge from hospital (on average, after 28 days), the following measures were compared between the group of patients with FM and the other patients: body weight, body mass index, functional independence (FIM), obesity-related disability (TSD-OC), self-reported functioning and the Timed-Up-Go (TUG) test. Thirty seven patients out of 130 fulfilled the diagnostic criteria for FM. The prevalence rate was 27.7% (95% CI: 20 to 35.4). Between-group comparisons showed that FM patients had higher disability level at the first assessment, had lower scores on the FIM at the final assessment, scored lower on self-reported functioning both at the first and the final assessments and had a lower body weight. The prevalence of FM in our study is much higher than the rates reported in the general normal-weight population (on average, 3.5%) and the 5.15% rate previously reported in a bariatric population. Functional data showed that the FM obese group yielded lower performance capacity and higher disability level as compared to the non-FM obese group. However, due to the relatively small sample size and the selected population, such results need to be confirmed in larger obese subpopulations.
近期有研究表明纤维肌痛(FM)与肥胖之间可能存在联系,但关于肥胖人群中FM患病率的可用数据非常匮乏。本横断面研究的目的是:1)评估接受康复治疗的肥胖患者群体中FM的患病率;2)调查FM对肥胖患者功能能力的影响。130名因1个月康复治疗而入院的意大利肥胖患者(体重指数,BMI≥30)参与了本研究。所有参与者均由一名风湿病学家根据2010年美国风湿病学会(ACR)FM诊断标准进行访谈。在入院时和出院时(平均28天后),比较了FM患者组和其他患者组之间的以下指标:体重、体重指数、功能独立性(FIM)、肥胖相关残疾(TSD-OC)、自我报告的功能以及计时起立行走(TUG)测试。130名患者中有37名符合FM诊断标准。患病率为27.7%(95%置信区间:20%至35.4%)。组间比较显示,FM患者在首次评估时残疾水平较高,在最终评估时FIM得分较低,在首次和最终评估时自我报告的功能得分均较低,且体重较轻。我们研究中FM的患病率远高于一般正常体重人群报告的患病率(平均3.5%)以及先前在肥胖症患者群体中报告的5.15%的患病率。功能数据表明,与非FM肥胖组相比,FM肥胖组的表现能力较低,残疾水平较高。然而,由于样本量相对较小且人群经过选择,这些结果需要在更大的肥胖亚群体中得到证实。