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Urinary levels of biogenic amine metabolites in mentally retarded children.

作者信息

Nalini K, Aroor A R, Rao A

机构信息

Department of Clinical Biochemistry, Kasturba Medical College, Karnataka, India.

出版信息

J Ment Defic Res. 1988 Oct;32 ( Pt 5):419-24. doi: 10.1111/j.1365-2788.1988.tb01432.x.

Abstract

Urinary total catecholamines, their metabolites and metabolite of serotonin were estimated in 32 mentally retarded children and 15 controls. Levels of total catecholamines. MHPG and 5-HIAA were not significantly different from controls. However, the mean VMA and HVA excretion in mentally retarded children was significantly increased compared to the control group. It is concluded that an altered metabolism of dopamine is involved in mental retardation.

摘要

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