Taddei I M, Ludin H P
Neurologische Universitätsklinik, Bern.
Schweiz Arch Neurol Psychiatr (1985). 1988;139(6):33-46.
41 patients who had been diagnosed as having essential tremor at least two years previously have been controlled. In 39 cases this diagnosis was confirmed. One patient was completely symptom-free after bilateral thalamotomy and another patient was now considered to have Parkinson's disease which had been discussed already four years before. 61% of the patients gave a positive family history for essential tremor, only two had non-first degree relatives suffering from Parkinson's disease. The present study does not provide any evidence for a correlation between essential tremor and Parkinson's disease. However, it should be noted that discrete other "extrapyramidal" signs may occasionally be found in patients having essential tremor.
41例至少在两年前被诊断为特发性震颤的患者已得到控制。其中39例确诊为此病。1例患者在双侧丘脑切开术后完全无症状,另1例患者现被认为患有帕金森病,而该病早在4年前就已被讨论过。61%的患者有特发性震颤的阳性家族史,只有2例有患帕金森病的非一级亲属。本研究未提供任何证据表明特发性震颤与帕金森病之间存在关联。然而,应当指出的是,特发性震颤患者偶尔可能会出现其他离散的“锥体外系”体征。