Canadian Center for Vaccinology, IWK Health Centre and Capital Health, Dalhousie University, Halifax, Nova Scotia, Canada.
Euro Surveill. 2014 Mar 6;19(9):20729. doi: 10.2807/1560-7917.es2014.19.9.20729.
During the 2013/14 influenza season in Canada, 631 of 654 hospitalisations for laboratory-confirmed influenza enrolled in sentinel hospitals were due to Influenza A. Of the 375 with known subtype, influenza A(H1N1) accounted for 357. Interim unmatched vaccine effectiveness adjusted for age and presence of one or more medical comorbidities was determined by test-negative case-control design to be 58.5% (90% confidence interval (CI): 43.9-69.3%) overall and 57.9% (90% CI: 37.7-71.5) for confirmed influenza A(H1N1).
在 2013/14 年加拿大流感季节期间，在哨点医院登记的 654 例实验室确诊流感住院病例中，有 631 例是由于甲型流感。在已知亚型的 375 例中，甲型 H1N1 流感占 357 例。采用病例对照试验设计，对年龄和是否存在一种或多种合并症进行调整后，临时未匹配的疫苗有效性为 58.5%（90%置信区间：43.9-69.3%），整体确诊的甲型 H1N1 流感疫苗有效性为 57.9%（90%置信区间：37.7-71.5%）。
