纳米羟基磷灰石对运动饮料致牙侵蚀的预防作用：原位研究
Prevention of dental erosion of a sports drink by nano-sized hydroxyapatite in situ study.
作者信息
Min Ji Hyun, Kwon Ho Keun, Kim Baek Il
机构信息
Department of Preventive Dentistry and Public Oral Health, Oral Science Research Institute, BK 21 Plus Project, Yonsei University College of Dentistry, Seoul, South Korea.
出版信息
Int J Paediatr Dent. 2015 Jan;25(1):61-9. doi: 10.1111/ipd.12101. Epub 2014 Mar 17.
AIM
To evaluate the inhibitory effects of the sports drink containing nano-sized hydroxyapatite (nano-HA) on dental erosion in situ.
DESIGN
The study had a single-blind, two-treatment crossover design. The two treatment groups were a control group (CG; Powerade only) and an experimental group (EG; 0.25% wt/vol nano-HA was added to Powerade). Ten subjects wore removable palatal appliances containing bovine enamel specimens. The appliances were immersed in each drink for 10 mins, 4 times a day for 10 days. The tooth surface microhardness (SMH) was tested, and the erosion depth and the morphology of the tooth surface were observed. The data were analysed by repeated measures anova and t-test.
RESULTS
Between the baseline and the 10th day, SMH was decreased by 80% in the specimens of the CG (P < 0.001), whereas there was only a 6% decrease in the SMH of the specimens in the EG. An erosion depth of 12.70 ± 4.66 μm and an irregular tooth surface were observed on the 10th day in the specimens of the CG. No dental erosions, however, was observed in the specimens of the EG.
CONCLUSIONS
The sports drink containing 0.25% nano-HA was effective in preventing dental erosion in situ.
目的
评估含纳米级羟基磷灰石（nano-HA）的运动饮料对原位牙侵蚀的抑制作用。
设计
本研究采用单盲、双处理交叉设计。两个处理组分别为对照组（CG；仅饮用沛绿雅运动饮料）和实验组（EG；在沛绿雅运动饮料中添加0.25%重量/体积的nano-HA）。10名受试者佩戴含有牛牙釉质标本的可摘腭部矫治器。将矫治器每天4次浸入每种饮料中10分钟，持续10天。测试牙齿表面显微硬度（SMH），并观察牙齿表面的侵蚀深度和形态。数据采用重复测量方差分析和t检验进行分析。
结果
在基线期和第10天之间，CG组标本的SMH下降了80%（P < 0.001），而EG组标本的SMH仅下降了6%。在第10天，CG组标本观察到侵蚀深度为12.70±4.66μm，牙齿表面不规则。然而，EG组标本未观察到牙侵蚀。
结论
含0.25% nano-HA的运动饮料对原位预防牙侵蚀有效。
Zotero 插件