对特应性皮炎患者进行卵形粉尘螨抗原的特应性斑贴试验。
Atopy patch test with Aleuroglyphus ovatus antigen in patients with atopic dermatitis.
作者信息
Lorenzini D, Pires M, Aoki V, Takaoka R, Souza R L, Vasconcellos C
机构信息
Dermatology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
出版信息
J Eur Acad Dermatol Venereol. 2015 Jan;29(1):38-41. doi: 10.1111/jdv.12429. Epub 2014 Mar 13.
BACKGROUND
Epicutaneous test made with dust mite antigens.
OBJECTIVE
Evaluation of the response of the epicutaneous test with Aleuroglyphus ovatus antigen in atopic patients.
METHODS
We patch tested 119 individuals, 48 with atopic dermatitis, 50 with respiratory allergy and 21 healthy controls. We compare the positive response frequency to a closed patch test using Aleuroglyphus ovatus antigen in different concentrations and 48 and 96h reading times among those individuals.
RESULTS
Six patients with atopic dermatitis (12.5%) and 4 with respiratory atopy (8.0%) had positive reactions. None of the non-atopic controls had a positive response. As the antigen concentration raised, the number of positive reactions to epicutaneous test raised as well.
CONCLUSION
Our data suggest a positive relation between Atopy Patch Test positive responses and Aleuroglyphus ovatus antigen concentration, no matter the kind of the atopic clinical expression.
背景
用尘螨抗原进行皮肤点刺试验。
目的
评估卵形嗜木螨抗原皮肤点刺试验在特应性患者中的反应。
方法
我们对119名个体进行了斑贴试验，其中48名患有特应性皮炎，50名患有呼吸道过敏，21名作为健康对照。我们比较了这些个体中使用不同浓度卵形嗜木螨抗原进行封闭斑贴试验在48小时和96小时读数时的阳性反应频率。
结果
6名特应性皮炎患者（12.5%）和4名呼吸道特应性患者（8.0%）出现阳性反应。非特应性对照均无阳性反应。随着抗原浓度升高，皮肤点刺试验的阳性反应数量也增加。
结论
我们的数据表明，无论特应性临床表现的类型如何，特应性斑贴试验阳性反应与卵形嗜木螨抗原浓度之间存在正相关。
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