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在一家肺科诊所连续就诊的681名患者群体中对慢性阻塞性肺疾病评估测试(CAT问卷)的敏感性进行调查:意大利的首个专项研究。

Sensitivity of the COPD assessment test (CAT questionnaire) investigated in a population of 681 consecutive patients referring to a lung clinic: the first Italian specific study.

作者信息

Dal Negro Roberto W, Bonadiman Luca, Turco Paola

机构信息

Research & Clinical Governance, Verona, Italy.

出版信息

Multidiscip Respir Med. 2014 Mar 15;9(1):15. doi: 10.1186/2049-6958-9-15.

Abstract

BACKGROUND

Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality at global level even if still underestimated. The insufficient use of specific tools for an objective definition and staging, the inadequate awareness of COPD, but also a difficult patient-to-doctor communication, can contribute to the poor management of COPD. A very simple, short and sensitive questionnaire (the "COPD Assessment Test" - CAT questionnaire) is now available for assessing the impact of COPD on the patient's health. The present study was designed to provide such evidence using data generated throughout Italy.

METHODS

The Italian validated version of the CAT questionnaire was distributed to 681 consecutive COPD patients of different severity (males = 480), well matched for age, gender, smoking habit, geographical distribution, BMI, dyspnoea score and educational level. The CAT score variability was investigated vs all anagraphic, and clinical variables, and spirometric indices of lung function (regression). No Italian data are available to our knowledge on the CAT use, neither in General Medicine, nor in the specialist setting.

RESULTS

Data of this study confirmed that the CAT questionnaire is a sensitive, simple, and quick tool for assessing the respiratory status of COPD patients. The CAT score proved not conditioned by the patient's age, gender, body size, geographical origin, and educational level. It was inversely correlated with the spirometric values, even if not uniquely linked to them.

CONCLUSIONS

The CAT score does not represent a surrogate measurement of lung function: it is an instrument which focuses on different areas of respiratory health in COPD patients, thus providing an useful and objective tool for the long-term clinical and therapeutic monitoring of COPD patients in the specialist outpatient setting.

摘要

背景

慢性阻塞性肺疾病(COPD)是全球发病和死亡的主要原因,即便其仍未得到充分重视。用于客观定义和分期的特定工具使用不足、对COPD的认识不足,以及医患沟通困难,都可能导致COPD管理不善。现在有一种非常简单、简短且敏感的问卷(“慢性阻塞性肺疾病评估测试”——CAT问卷)可用于评估COPD对患者健康的影响。本研究旨在利用意大利各地收集的数据提供此类证据。

方法

将意大利语验证版的CAT问卷分发给681例连续的不同严重程度的COPD患者(男性480例),这些患者在年龄、性别、吸烟习惯、地理分布、体重指数、呼吸困难评分和教育水平方面匹配良好。研究了CAT评分与所有人口统计学、临床变量以及肺功能的肺量计指标之间的变异性(回归分析)。据我们所知,在意大利,无论是在普通医学还是专科环境中,都没有关于CAT使用情况的数据。

结果

本研究数据证实,CAT问卷是评估COPD患者呼吸状况的一种敏感、简单且快速的工具。CAT评分不受患者年龄、性别、体型、地理来源和教育水平的影响。它与肺量计值呈负相关,尽管并非唯一相关。

结论

CAT评分并非肺功能的替代测量指标:它是一种关注COPD患者呼吸健康不同领域的工具,从而为专科门诊环境中COPD患者的长期临床和治疗监测提供了一种有用且客观的工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4248/3977871/6d308dba3eda/2049-6958-9-15-1.jpg

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