Lopez-Campos Jose Luis, Fernandez-Villar Alberto, Calero-Acuña Carmen, Represas-Represas Cristina, Lopez-Ramírez Cecilia, Fernández Virginia Leiro, Soler-Cataluña Juan Jose, Casamor Ricard
Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocio/Universidad de Sevilla, Sevilla, Spain ; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Servicio de Neumología, Instituto de Investigación Biomédica de Vigo (IBIV), Complexo Hospitalario de Vigo, Vigo, Spain.
Int J Chron Obstruct Pulmon Dis. 2015 May 27;10:975-84. doi: 10.2147/COPD.S82781. eCollection 2015.
The COPD Assessment Test (CAT) has been recently developed to quantify COPD impact in routine practice. However, no relationship with other measures in the Global Initiative for Obstructive Lung Disease (GOLD) strategy has been evaluated. The present study aimed to evaluate the relationship of the CAT with other GOLD multidimensional axes, patient types, and the number of comorbidities.
This was a cross-sectional analysis of the Clinical presentation, diagnosis, and course of chronic obstructive pulmonary disease (On-Sint) study. The CAT score was administered to all participants at the inclusion visit. A GOLD 2011 strategy consisting of modified Medical Research Council scale (MRC) scores was devised to study the relationship between the CAT, and GOLD 2011 axes and patient types. The relationship with comorbidities was assessed using the Charlson comorbidity index, grouped as zero, one to two, and three or more.
The CAT questionnaire was completed by 1,212 patients with COPD. The CAT maintained a relationship with all the three axes, with a ceiling effect for dyspnea and no distinction between mild and moderate functional impairment. The CAT score increased across GOLD 2011 patient types A-D, with similar scores for types B and C. Within each GOLD 2011 patient type, there was a considerably wide distribution of CAT values.
Our study indicates a correlation between CAT and the GOLD 2011 classification axes as well as the number of comorbidities. The CAT score can help clinicians, as a complementary tool to evaluate patients with COPD within the different GOLD patient types.
慢性阻塞性肺疾病评估测试（CAT）最近已被开发出来，用于在日常实践中量化慢性阻塞性肺疾病（COPD）的影响。然而，尚未评估其与慢性阻塞性肺疾病全球倡议（GOLD）策略中其他指标的关系。本研究旨在评估CAT与GOLD其他多维指标、患者类型及合并症数量之间的关系。
这是一项关于慢性阻塞性肺疾病的临床表现、诊断及病程（On-Sint）研究的横断面分析。在纳入研究时，对所有参与者进行CAT评分。制定了一个由改良的医学研究委员会量表（MRC）评分组成的GOLD 2011策略，以研究CAT与GOLD 2011指标及患者类型之间的关系。使用Charlson合并症指数评估与合并症的关系，分为无、一至两种以及三种或更多。
1212例COPD患者完成了CAT问卷调查。CAT与所有三个指标均有关系，呼吸困难存在天花板效应，轻度和中度功能障碍之间无差异。CAT评分在GOLD 2011的A - D型患者中逐渐升高，B型和C型患者评分相似。在每种GOLD 2011患者类型中，CAT值分布相当广泛。
我们的研究表明CAT与GOLD 2011分类指标以及合并症数量之间存在相关性。CAT评分可作为一种辅助工具，帮助临床医生评估不同GOLD患者类型中的COPD患者。
