Rodriguez-Campos Sabrina, Smith Noel H, Boniotti Maria B, Aranaz Alicia
Institute of Veterinary Bacteriology, Veterinary Faculty, University of Bern, Laenggassstrasse 122, 3012 Bern, Switzerland.
Animal Health and Veterinary Laboratories Agency, Weybridge, New Haw, Addlestone, Surrey KT15 3NB, UK.
Res Vet Sci. 2014 Oct;97 Suppl:S5-S19. doi: 10.1016/j.rvsc.2014.02.009. Epub 2014 Feb 25.
Members of the Mycobacterium tuberculosis complex (MTBC) cause a serious disease with similar pathology, tuberculosis; in this review, bovine tuberculosis will be considered as disease caused by any member of the MTBC in bovids. Bovine tuberculosis is responsible for significant economic loss due to costly eradication programs and trade limitations and poses a threat to both endangered and protected species as well as to public health. We here give an overview on all members of the MTBC, focusing on their isolation from different animal hosts. We also review the recent advances made in elucidating the evolutionary and phylogenetic relationships of members of the MTBC. Because the nomenclature of the MTBC is controversial, its members have been considered species, subspecies or ecotypes, this review discusses the possible implications for diagnostics and the legal consequences of naming of new species.
结核分枝杆菌复合群（MTBC）的成员会引发一种具有相似病理特征的严重疾病——结核病；在本综述中，牛结核病将被视为由MTBC的任何成员在牛科动物中引起的疾病。由于昂贵的根除计划和贸易限制，牛结核病造成了重大经济损失，并对濒危和受保护物种以及公众健康构成威胁。我们在此概述MTBC的所有成员，重点关注它们从不同动物宿主中的分离情况。我们还回顾了在阐明MTBC成员的进化和系统发育关系方面取得的最新进展。由于MTBC的命名存在争议，其成员曾被视为物种、亚种或生态型，本综述讨论了这对诊断可能产生的影响以及新物种命名的法律后果。
