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婴幼儿血管瘤的诊断与治疗。

Diagnosis and management of infantile hemangiomas.

机构信息

Division of Pediatric Dermatology, Department of Dermatology, Johns Hopkins University School of Medicine, 200 North Wolfe Street, Unit 2107, Baltimore, MD 21287, USA.

出版信息

Pediatr Clin North Am. 2014 Apr;61(2):383-402. doi: 10.1016/j.pcl.2013.11.010. Epub 2014 Feb 18.

Abstract

Propranolol has replaced corticosteroids as preferred first-line therapy for the management of infantile hemangiomas (IH). The topical β-blocker timolol is now an alternative to oral propranolol and watchful waiting for smaller IH. Research in the last decade has provided evidence-based data about natural history, epidemiology, and syndromes associated with IH. The most pressing issue for the clinician treating children with IH is to understand current data to develop an individualized risk stratification for each patient and determine the likelihood of complications and need for treatment. This article emphasizes the nuances of complicated clinical presentations and current treatment recommendations.

摘要

普萘洛尔已取代皮质类固醇,成为治疗婴儿血管瘤(IH)的首选一线治疗药物。局部β受体阻滞剂噻吗洛尔现在是口服普萘洛尔和观察等待较小 IH 的替代方法。过去十年的研究为 IH 的自然史、流行病学和相关综合征提供了循证数据。治疗 IH 患儿的临床医生最紧迫的问题是了解现有数据,为每位患者制定个体化风险分层,并确定并发症发生的可能性和治疗需求。本文强调了复杂临床表现和当前治疗建议的细微差别。

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