Corradin Maria Teresa, Giulioni Erika, Fiorentino Renzo, Santeufemia Davide Adriano, Re Giovanni Lo, Vettorello Angelo
Dermatology Unit Azienda Ospedaliera Santa Maria degli Angeli, Pordenone, Padua, Italy. Anatomical Pathology Unit Azienda Ospedaliera Santa Maria degli Angeli, Pordenone, Padua, Italy. Oncology Unit Azienda Ospedaliera Santa Maria degli Angeli, Pordenone, Padua, Italy. Dermatologist Ambulatoriale Azienda Sanitaria n. 6 Friuli Occidentale, Pordenone, Padua, Italy. Corresponding author:
Acta Dermatovenerol Alp Pannonica Adriat. 2014 Mar;23(1):17-9.
Nevus spilus is the term usually given to a pigmented skin lesion, congenital or acquired, that may occur anywhere on the body, consisting of a large light tan patch with numerous superimposed darker scattered maculae or papulae that are flat or slightly raised. For a long time, nevus spilus was believed to be a benign lesion. However, in 1957 Perkinson reported a melanoma appearing on nevus spilus for the first time. Since then other reports about melanomas developing on nevus spilus have been published, sometimes with a fatal outcome. We describe the case of an 80-year-old male patient with a congenital nevus just above his left knee. The lesion had remained unchanged over time, but some months before his checkup the patient noticed a darker area in the lesion that had continued to enlarge. The lesion was removed and histological examination revealed an in situ malignant melanoma. Although nevus spilus is not normally considered a precursor of melanoma, the potentiality of malignant transformation requires regular monitoring, and careful checkups are recommended and justified.
斑痣是通常用于描述一种色素沉着性皮肤病变的术语，该病变可为先天性或后天性，可发生于身体的任何部位，表现为一大片浅棕褐色斑片，其上有许多散在的深色斑点或丘疹，这些斑点或丘疹可为扁平状或略隆起。长期以来，斑痣一直被认为是一种良性病变。然而，1957年珀金森首次报道了一例发生于斑痣上的黑色素瘤。从那时起，关于斑痣上发生黑色素瘤的其他报道也相继发表，有时会导致致命后果。我们描述了一例80岁男性患者，其左膝上方有一个先天性痣。该病变长期以来一直未变，但在他接受检查的几个月前，患者注意到病变内有一个较暗的区域，且该区域持续扩大。病变被切除，组织学检查显示为原位恶性黑色素瘤。尽管斑痣通常不被认为是黑色素瘤的前驱病变，但恶性转化的可能性需要定期监测，建议并合理进行仔细检查。
