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斑痣:基于激光的治疗方法综述

Nevus Spilus: A Review of Laser-Based Therapeutic Approaches.

作者信息

Alqahtani Jamal

机构信息

Department of Dermatology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Eastern Province, Saudi Arabia.

出版信息

Acta Inform Med. 2025;33(2):158-161. doi: 10.5455/aim.2025.33.158-161.

DOI:10.5455/aim.2025.33.158-161
PMID:40606239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12212278/
Abstract

BACKGROUND

Nevus spilus (NS) is a congenital melanocytic nevus with specific clinical characteristics. The condition generally appears in the first year of life and shows no gender preference while affecting individuals with lighter skin tones. It has a predilection for lower limbs and trunk areas the NS lesions consist of tiny heavily pigmented papules and macules accumulated on a well-bordered, lighter brown macular backdrop, comparable to a café-au-lait macule, frequently along Blaschko lines. The type of nevus has been reported as a blue nevus, centrofacial lentiginosis, nevus sebaceous, and bilateral nevus of Ito.

OBJECTIVE

To highlight laser options for nevus spilus.

METHODS

A review of various laser-based treatment modalities was conducted, focusing on their application in NS. The lasers included Q-switched ruby (QSRL), alexandrite (QSAL), Nd:YAG 532 and 1064 nm, carbon dioxide (CO2), intense pulsed light (IPL), and pulsed dye laser (PDL).

RESULTS AND DISCUSSION

The laser modalities have shown varying degrees of success in improving the appearance of NS lesions. The QSRL, QSAL and QSNYL lasers are commonly used because they are specific for melanin. Ablative lasers like CO2 and broad-spectrum devices like IPL and PDL have also been employed, each offering different advantages depending on lesion characteristics and treatment goals.

CONCLUSION

Regular monitoring for suspicious malignant degeneration should be done and if any signs of melanoma are present, histological examination is warranted. While no treatment is usually necessary, surgery has been proposed to eliminate the risk of melanoma. Aside from surgical management, various lasers have been tried to treat NS with varied success. QSRL, QSAL, QSNYL 532, and 1064 nm, CO2, IPL and PDL have all been demonstrated to improve NS.

摘要

背景

斑痣(NS)是一种具有特定临床特征的先天性黑素细胞痣。该病通常在出生后第一年出现,无性别差异,多见于肤色较浅的个体。它好发于下肢和躯干,NS 损害由微小的、色素沉着明显的丘疹和斑疹组成,聚集在边界清晰、浅棕色的斑片状背景上,类似于咖啡牛奶斑,常沿 Blaschko 线分布。这种痣曾被报道为蓝痣、面部中央雀斑样痣、皮脂腺痣和伊藤双侧痣。

目的

强调斑痣的激光治疗选择。

方法

对各种基于激光的治疗方式进行综述,重点关注其在 NS 中的应用。所涉及的激光包括 Q 开关红宝石激光(QSRL)、翠绿宝石激光(QSAL)、532 和 1064 纳米的 Nd:YAG 激光、二氧化碳(CO2)激光、强脉冲光(IPL)和脉冲染料激光(PDL)。

结果与讨论

激光治疗方式在改善 NS 损害外观方面取得了不同程度的成功。QSRL、QSAL 和 QSNYL 激光因其对黑色素具有特异性而常用。像 CO2 这样的剥脱性激光以及像 IPL 和 PDL 这样的广谱设备也已被应用,每种根据损害特征和治疗目标都有不同优势。

结论

应定期监测是否有可疑的恶性变,如果出现任何黑色素瘤迹象,有必要进行组织学检查。虽然通常无需治疗,但有人建议手术以消除黑色素瘤风险。除手术治疗外,已尝试多种激光治疗 NS,效果各异。QSRL、QSAL、QSNYL 532 和 1064 纳米、CO2、IPL 和 PDL 均已证明可改善 NS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655d/12212278/3d92acc8b698/AIM-33-158-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655d/12212278/3d92acc8b698/AIM-33-158-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655d/12212278/3d92acc8b698/AIM-33-158-g001.jpg

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