Timofeeva E V, Liashchenko O Ia
Vestn Ross Akad Med Nauk. 2013(10):53-6.
In the article analyzed the current literature, devoted to the peculiarities of functioning of the thyroid gland in patients with HIV infection. Based on the analysis of literature data bases demonstrated the structure of thyroid function disorders in HIV-infected, as well as the mechanisms of the pathogenesis of these disorders. In the structure of thyroid function is dominated by hypothyroidism, euthyroid pathological syndrome, Graves' disease, for which the opportunistic infections are triggers immune activation. It should be noted that the step of acquired immunodeficiency syndrome is accompanied by the development of inflammatory and neoplastic processes in the thyroid gland. Convincingly demonstrated the negative impact of highly active antiretroviral therapy in HIV-positive for the development of thyroid dysfunction, in connection which the expediency of forming risk groups and the timely correction of the projected thyroid diseases.
在这篇文章中，分析了当前致力于HIV感染患者甲状腺功能特点的文献。基于对文献数据库的分析，展示了HIV感染者甲状腺功能障碍的结构以及这些障碍的发病机制。在甲状腺功能结构中，以甲状腺功能减退、甲状腺功能正常的病理综合征、格雷夫斯病为主，机会性感染是这些疾病免疫激活的触发因素。应该指出的是，获得性免疫缺陷综合征阶段伴随着甲状腺的炎症和肿瘤过程的发展。令人信服地证明了高效抗逆转录病毒疗法对HIV阳性患者甲状腺功能障碍发展的负面影响，因此形成风险群体并及时纠正预计的甲状腺疾病是合理的。
