[Effect of daily immunization and antirabies gamma-globulin on the development of immune T-killers in inbred mice infected with the street rabies virus].

Daily administration of vaccine as well as combined use of antirabies gamma-globulin and vaccine were shown not to induce the production of immune T-killers possessing protective properties in adoptive transfer in mice pre-infected with street rabies virus in contrast to a single administration of a shock dose of antigen. Immune splenocytes protected 31-43% of mice infected with street rabies virus in a dose of 2-4 im LD50 and did not protect the animals infected with a dose of 12 im-LD50. After combined administration of immune splenocytes and an interferon inducer (double-stranded RNA) the additive protective effect was observed.