Fink-Jensen A, Mikkelsen J D
Department B, University of Copenhagen, Denmark.
Brain Res. 1989 Jan 2;476(1):194-8. doi: 10.1016/0006-8993(89)91558-8.
The projection from the caudate-putamen to the entopeduncular nucleus was studied in rats using the wheatgerm-agglutinin--horseradish peroxidase (WGA-HRP) tracing technique. After iontophoretic injections of WGA-HRP into subregions of the entopeduncular nucleus, numerous HRP-labeled cells were found in the ipsilateral caudate-putamen. In all cases, the labeled neurons were localized in a restricted part of the caudate-putamen rostral to the cross-over of the anterior commissure. Labeled cells in the nucleus accumbens or the olfactory tubercle were never observed. The striato-entopeduncular projection was topographically organized: dorsal caudate-putamen projects to the dorsal part of the entopeduncular nucleus and ventral caudate-putamen to the ventral part. These results demonstrate that the striato-entopeduncular pathway is topographically organized as are a number of other neuronal circuits of the basal ganglia system.
利用小麦胚凝集素-辣根过氧化物酶（WGA-HRP）追踪技术，对大鼠尾状核-壳核向内侧苍白球核的投射进行了研究。在将WGA-HRP离子导入内侧苍白球核的各亚区后，在同侧尾状核-壳核中发现了大量HRP标记的细胞。在所有情况下，标记的神经元都位于前连合交叉前方尾状核-壳核的一个局限区域内。从未观察到伏隔核或嗅结节中有标记细胞。纹状体-内侧苍白球核投射在拓扑学上是有组织的：尾状核-壳核背侧投射到内侧苍白球核的背侧部分，腹侧投射到腹侧部分。这些结果表明，纹状体-内侧苍白球核通路在拓扑学上的组织方式与基底神经节系统的许多其他神经元回路相同。
