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未分化多形性肉瘤：病例报告

Undifferentiated Pleomorphic Sarcoma: A Case Report.

作者信息

Munuswamy Nivetha, Sundar Madan, Krishnan Kuberan, Chandran Magesh, R K Karpagam

机构信息

Department of General Surgery, Sree Balaji Medical College & Hospital, Chennai, IND.

Department of Radiology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University, Chennai, IND.

出版信息

Cureus. 2024 Nov 11;16(11):e73422. doi: 10.7759/cureus.73422. eCollection 2024 Nov.

DOI:10.7759/cureus.73422
PMID:39664140
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11632629/
Abstract

Undifferentiated pleomorphic sarcoma (UPS) is an uncommon and aggressive soft tissue tumor primarily affecting older adults, often presenting as a rapidly enlarging, painless mass in the extremities or other deep-seated locations. This case involves a 55-year-old woman who experienced a rapidly progressive and painful swelling in her right thigh following trauma. Imaging studies identified a large, lobulated tumor in the adductor muscles, close to the femur and pubic ramus, with no bone involvement or evidence of distant metastasis. The patient underwent surgical excision, and histopathological analysis confirmed high-grade UPS, necessitating adjuvant radiotherapy due to narrow surgical margins. Follow-up evaluations, including MRI scans at six months and one year, revealed no signs of disease recurrence. The case underscores the critical role of early detection, multidisciplinary treatment planning, and rigorous postoperative monitoring to improve outcomes and reduce the risk of recurrence in patients with UPS.

摘要

未分化多形性肉瘤（UPS）是一种罕见且侵袭性的软组织肿瘤，主要影响老年人，常表现为四肢或其他深部部位迅速增大的无痛性肿块。该病例涉及一名55岁女性，她在受伤后右大腿出现迅速进展且疼痛的肿胀。影像学检查发现内收肌有一个大的分叶状肿瘤，靠近股骨和耻骨支，无骨质受累或远处转移证据。患者接受了手术切除，组织病理学分析证实为高级别UPS，由于手术切缘狭窄，需要辅助放疗。包括术后6个月和1年的MRI扫描在内的随访评估显示无疾病复发迹象。该病例强调了早期检测、多学科治疗规划以及严格的术后监测在改善UPS患者预后和降低复发风险方面的关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/fa6315a2be6b/cureus-0016-00000073422-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/6432b789500d/cureus-0016-00000073422-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/f2c7d3e5c9d9/cureus-0016-00000073422-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/3408a99324a1/cureus-0016-00000073422-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/4058ef6455e8/cureus-0016-00000073422-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/f5551d3d1f2b/cureus-0016-00000073422-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/5c536641a395/cureus-0016-00000073422-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/fa6315a2be6b/cureus-0016-00000073422-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/6432b789500d/cureus-0016-00000073422-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/f2c7d3e5c9d9/cureus-0016-00000073422-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/3408a99324a1/cureus-0016-00000073422-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/4058ef6455e8/cureus-0016-00000073422-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/f5551d3d1f2b/cureus-0016-00000073422-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/5c536641a395/cureus-0016-00000073422-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/11632629/fa6315a2be6b/cureus-0016-00000073422-i07.jpg

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本文引用的文献

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A retroperitoneal primary undifferentiated pleomorphic sarcoma.一例腹膜后原发性未分化多形性肉瘤。
Urol Case Rep. 2024 Jan 20;53:102664. doi: 10.1016/j.eucr.2024.102664. eCollection 2024 Mar.
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UNDIFFERENTIATED PLEOMORPHIC SARCOMA: PROGNOSTIC FACTORS IN 42 EXTREMITY CASES.未分化多形性肉瘤：42例肢体病例的预后因素
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