Katake Yoshiki, Ichikawa Kazuhito, Fujio Chikau, Tomita Shigeki, Imura Johji, Fujimori Takahiro
Katake Clinic (Ichouka Naika), Hyogo;
Department of Surgical and Molecular Pathology, Dokkyo Medical University School of Medicine, Tochigi;
Biomed Rep. 2013 Jan;1(1):23-27. doi: 10.3892/br.2012.8. Epub 2012 Sep 3.
The aim of this study was to evaluate the significance of an endoscopic atrophic border and irregular arrangement of collecting venules (IRAC) in the diagnosis of ()-induced gastritis. Upper gastrointestinal tract endoscopy was performed on 723 patients, who were screened them for infection. Any patients who had undergone eradication therapy were excluded from the study. The endoscopic atrophic border and IRAC in each patient were assessed. The status was determined in the patients by combination of a serological test and/or histopathological examination. The infection rates were 95.4% (455/477) in the group with an endoscopic atrophic border and 22.3% (55/246) in the group without an endoscopic atrophic border. In the diagnostic validity check, presence of an endoscopic atrophic border had a sensitivity of 89.2% and a specificity of 89.7%. Furthermore, the infection rates were 95.5% (506/530) in the IRAC group and 2.1% (4/193) in the regular arrangement of collecting venules (RAC) group. In the diagnostic validity check, IRAC had a sensitivity of 99.2% and a specificity of 88.7%. In conclusion, the presence of an endoscopic atrophic border and IRAC are highly indicative of an -infected gastric mucosa.
本研究的目的是评估内镜下萎缩边界和集合小静脉不规则排列(IRAC)在诊断()诱导的胃炎中的意义。对723例患者进行了上消化道内镜检查,并对他们进行了感染筛查。任何接受过根除治疗的患者均被排除在研究之外。评估了每位患者的内镜下萎缩边界和IRAC。通过血清学检测和/或组织病理学检查相结合的方式确定患者的状态。内镜下有萎缩边界的组感染率为95.4%(455/477),无内镜下萎缩边界的组感染率为22.3%(55/246)。在诊断有效性检查中,内镜下存在萎缩边界的敏感性为89.2%,特异性为89.7%。此外,IRAC组的感染率为95.5%(506/530),集合小静脉规则排列(RAC)组的感染率为2.1%(4/193)。在诊断有效性检查中,IRAC的敏感性为99.2%,特异性为88.7%。总之,内镜下萎缩边界和IRAC的存在高度提示胃黏膜感染。 (注:原文括号处内容缺失)