Alaboudy Alshimaa, Elbahrawy Ashraf, Matsumoto Shigemi, Galal Ghada M, Chiba Tsutomu
Alshimaa Alaboudy, Ashraf Elbahrawy, Shigemi Matsumoto, Tsutomu Chiba, Department of Endoscopy, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
World J Gastrointest Endosc. 2011 Jun 16;3(6):118-23. doi: 10.4253/wjge.v3.i6.118.
To address the diagnostic value of the regular arrangement of collecting venules (RAC) among old age patients.
A total of 390 consecutive patients whose Helicobacter pylori (H. pylori) status was known and who received upper gastrointestinal endoscopy, were retrospectively studied for the presence or absence of RAC as well as gastric mucosal atrophy. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of RAC to detect normal gastric mucosa were assessed and were compared among two different age groups of patients.
The mean age ± standard deviation (SD) of included patients (n = 390), was 62.9 ± 13 years. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of RAC to detect normal gastric mucosa were 91.7%, 66.1%, 18.8%, 99% and 68.1% respectively. Although the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of RAC among patients < 60 years (n = 139) was 94.7%, 71.2%, 46.2%, 98.1%and 76.1%, respectively, it was 80%, 64.3%, 5.1%, 93% and 64.6%, respectively, among patients ≥ 60 years (n = 251). Younger Patients (< 60 years), have highly significant rates of RAC sensitivity, positive predictive value, and accuracy (P ≤ 0.001, ≤ 0.001 and ≤ 0.02, respectively). Older patients had highly significant rates of H. pylori infection and gastric mucosal atrophy (P ≤ 0.01).
Although RAC is a valuable sign for real-time identification of normal gastric mucosa, its accuracy seems to be affected by the patient's age.
探讨老年患者中集合小静脉规则排列(RAC)的诊断价值。
对390例连续接受上消化道内镜检查且已知幽门螺杆菌(H. pylori)感染状态的患者进行回顾性研究,观察有无RAC以及胃黏膜萎缩情况。评估RAC检测正常胃黏膜的敏感性、特异性、阳性预测值、阴性预测值和准确性,并在两个不同年龄组患者中进行比较。
纳入患者(n = 390)的平均年龄±标准差(SD)为62.9±13岁。RAC检测正常胃黏膜的敏感性、特异性、阳性预测值、阴性预测值和准确性分别为91.7%、66.1%、18.8%、99%和68.1%。虽然年龄<60岁患者(n = 139)中RAC的敏感性、特异性、阳性预测值、阴性预测值和准确性分别为94.7%、71.2%、46.2%、98.1%和76.1%,但年龄≥60岁患者(n = 251)中分别为80%、64.3%、5.1%、93%和64.6%。较年轻患者(<60岁)的RAC敏感性、阳性预测值和准确性有高度显著差异(P分别≤0.001、≤0.001和≤0.02)。老年患者的幽门螺杆菌感染率和胃黏膜萎缩率有高度显著差异(P≤0.01)。
虽然RAC是实时识别正常胃黏膜的一个有价值的征象,但其准确性似乎受患者年龄影响。