Coit D G, Brennan M F
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York.
Arch Surg. 1989 Feb;124(2):162-6. doi: 10.1001/archsurg.1989.01410020032004.
The extent of lymph node dissection necessary to optimize survival and minimize local recurrence in patients with melanoma of the trunk or lower extremity is not well defined. We reviewed the records of 420 patients undergoing superficial or combined superficial and deep groin dissection for melanoma. Prognosis depended on the extent of lymph node involvement rather than the extent of surgery performed. Node-positive patients undergoing elective lymph node dissection had an improved survival over those undergoing therapeutic lymph node dissection. In no subgroup of patients was more extensive lymphadenectomy associated with significant improvement in survival or alteration in pattern of recurrence. Dissection of the deep pelvic nodes in patients with melanoma appears to be of more prognostic than therapeutic value.
对于躯干或下肢黑色素瘤患者,为优化生存率并将局部复发降至最低所需的淋巴结清扫范围尚不清楚。我们回顾了420例行浅表或浅表与深部腹股沟联合清扫术治疗黑色素瘤患者的记录。预后取决于淋巴结受累程度,而非手术范围。接受择期淋巴结清扫术的淋巴结阳性患者比接受治疗性淋巴结清扫术的患者生存率更高。在任何亚组患者中,更广泛的淋巴结切除术都未带来生存率的显著提高或复发模式的改变。黑色素瘤患者的盆腔深部淋巴结清扫似乎具有更多的预后价值而非治疗价值。