Kosmidis Christoforos, Efthimiadis Christoforos, Anthimidis Georgios, Grigoriou Marios, Vasiliadou Kalliopi, Ioannidou Georgia, Makedou Fotini, Baka Sofia
Department of Surgery, Interbalkan European Medical Center, 84 Tsimiski Street, 54622 Thessaloniki, Greece.
Case Rep Med. 2011;2011:670581. doi: 10.1155/2011/670581. Epub 2011 Apr 6.
Background. Malignant melanoma incidence is increasing dramatically. We report herein a case of the rarest acral lentiginous type. Case Report. A 58-year-old man presented with a melanoma resembling lesion over the sole of his right foot, measuring 15-20 mm in diameter. An excisional biopsy with a narrow (2 mm) margin of surrounding skin was obtained. Histological findings were consistent with a diagnosis of acral lentiginous melanoma. Sentinel lymph node biopsy was also performed and micrometastases were not identified in frozen-section examination. According to the AJCC system, the tumor stage was IB (T2aN0M0). A wide local excision of the biopsy scar with a margin of 2 cm was performed. A split-thickness thick skin graft was used to reconstruct the excisional defect. During an 18-month followup, no local or distant recurrence has been observed. This paper aims to extract an updated rational approach to the management of this disease out of an enormous body of knowledge.
背景。恶性黑色素瘤的发病率正在急剧上升。我们在此报告一例极为罕见的肢端雀斑样痣型病例。病例报告。一名58岁男性，其右脚足底出现一个类似黑色素瘤的皮损，直径为15 - 20毫米。进行了切除活检，周围皮肤切缘狭窄（2毫米）。组织学检查结果符合肢端雀斑样痣型黑色素瘤的诊断。同时也进行了前哨淋巴结活检，冰冻切片检查未发现微转移。根据美国癌症联合委员会（AJCC）系统，肿瘤分期为IB期（T2aN0M0）。对活检瘢痕进行了切缘为2厘米的广泛局部切除。采用中厚皮片移植来修复切除后的缺损。在18个月的随访期间，未观察到局部或远处复发。本文旨在从大量知识中提炼出一种针对该疾病治疗的最新合理方法。
