Tontini Gian Eugenio, Bisschops Raf, Neumann Helmut
Department of Medicine 1, University of Erlangen-Nuremberg, Ulmenweg 18, 91054 Erlangen, Germany.
Expert Rev Gastroenterol Hepatol. 2014 Jul;8(5):543-54. doi: 10.1586/17474124.2014.899899. Epub 2014 Mar 20.
Endoscopy plays a pivotal role for diagnosis and assessment of disease activity and extent in patients with inflammatory bowel diseases. International guidelines recommend the use of endoscopic scoring systems for evaluation of the prognosis and efficacy of medical treatments. Ideal scoring systems are easy to use, reproducible, reliable, responsive to changes, and validated in different clinical settings in order to guide therapeutic strategies. However, currently available endoscopic scoring systems often appear as complex for routine endoscopy and suffer from insufficient interobserver agreement and lack of formal validation which often limit their use in clinical trials. Here, we describe the role of endoscopic scoring systems in inflammatory bowel diseases focusing on pros and cons in the era of advanced endoscopic imaging and mucosal healing.
内镜检查在炎症性肠病患者的疾病诊断、活动度及范围评估中发挥着关键作用。国际指南推荐使用内镜评分系统来评估药物治疗的预后和疗效。理想的评分系统应易于使用、可重复、可靠、对变化有反应，并在不同临床环境中得到验证，以指导治疗策略。然而，目前可用的内镜评分系统对于常规内镜检查而言往往显得复杂，观察者间一致性不足且缺乏正式验证，这常常限制了它们在临床试验中的应用。在此，我们描述内镜评分系统在炎症性肠病中的作用，重点关注先进内镜成像和黏膜愈合时代的优缺点。
