Yunis Juan J, Acevedo Luis E, Campo David S, Yunis Emilio J
Departamento de Patología, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D.C, Colombia.
Departamento de Biología, Facultad de Ciencias, Universidad Nacional de Colombia, Bogotá, D.C, Colombia.
Biomedica. 2013 Jul-Sep;33(3):459-67. doi: 10.7705/biomedica.v33i3.807.
Y chromosome STR haplotypes have been widely used in population studies to establish the origin of diverse populations.
We analyzed Y chromosome STR haplotypes (8 loci) in 134 Caucasian-mestizo and 137 African-descent Colombian unrelated individuals to correlate the geographical origin with historical data as well as the genetic relationships and possible admixture patterns.
One hundred samples of African descent and 137 Caucasian-mestizo samples analyzed for Y chromosome STR haplotypes by PCR followed by acrylamide electrophoresis.
No evidence of population substructure was found for the African descent. Two point fifty nine per cent of the haplotypes were shared between the two groups with the possible existence of Caucasian gene flow towards Afro-descendants.
The Caucasian-Mestizo Colombian population is grouped with other populations of the Iberian Peninsula and Europe, while the Afro-Colombian population is grouped with other African populations reported.
Y染色体短串联重复序列（STR）单倍型已广泛应用于群体研究，以确定不同群体的起源。
我们分析了134名高加索 - 梅斯蒂索人和137名非洲裔哥伦比亚无关个体的Y染色体STR单倍型（8个位点），以将地理起源与历史数据以及遗传关系和可能的混合模式相关联。
通过PCR随后进行丙烯酰胺电泳分析了100份非洲裔样本和137份高加索 - 梅斯蒂索样本的Y染色体STR单倍型。
未发现非洲裔群体存在群体亚结构的证据。两组之间有2.59%的单倍型是共享的，可能存在高加索人向非洲后裔的基因流动。
哥伦比亚的高加索 - 梅斯蒂索人群体与伊比利亚半岛和欧洲的其他群体归为一类，而非洲裔哥伦比亚人群体与报道的其他非洲群体归为一类。
