Stabile I, Olajide F, Chard T, Grudzinskas J G
Joint Academic Unit of Obstetrics and Gynaecology and Reproductive Physiology, Medical College, London Hospital, UK.
Hum Reprod. 1989 Feb;4(2):204-5. doi: 10.1093/oxfordjournals.humrep.a136873.
Maternal serum alpha-fetoprotein (AFP) levels were determined in 21 women with threatened miscarriage in whom an ultrasound diagnosis of anembryonic pregnancy was confirmed. Fourteen of the 21 patients had normal AFP levels; the remaining seven had levels above the 95th centile of the reference range. This is in contrast to earlier findings of an association between low levels of AFP in anembryonic pregnancy. It is concluded that most anembryonic pregnancies are pregnancies in which the fetus has been lost rather than pregnancies in which the fetus was never present.
对21例有先兆流产且超声确诊为空孕囊妊娠的孕妇测定了母血清甲胎蛋白（AFP）水平。21例患者中有14例AFP水平正常；其余7例的水平高于参考范围的第95百分位数。这与早期关于空孕囊妊娠中AFP水平低之间存在关联的研究结果相反。得出的结论是，大多数空孕囊妊娠是胎儿已丢失的妊娠，而非胎儿从未存在的妊娠。
